THE ANTIBACTERIAL ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL.) URB.) FROM CENTRAL KALIMANTAN AGAINST ACNE-CAUSING BACTERIA

  • SUSI NOVARYATIIN Department of Pharmacy, Faculty of Health Science, Universitas Muhammadiyah Palangkaraya, Palangka Raya, Central Kalimantan, Indonesia
  • SYAHRIDA DIAN ARDHANY Department of Pharmacy, Faculty of Health Science, Universitas Muhammadiyah Palangkaraya, Palangka Raya, Central Kalimantan, Indonesia

Abstract

Objective: The objective of this research was to investigate the antibacterial activity of bawang dayak from Central Kalimantan against acne-causing
bacteria namely Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus.
Methods: The preliminary phytochemical constituents were qualitatively analyzed. Antibacterial activity of bawang dayak ethanol extract was
performed using disc-diffusion technique, with five variations of concentration of 1.25%, 2.5%, 5%, 10%, and 20%.
Results: Bawang dayak extract contained flavonoids, alkaloids, saponins, and tannins. The inhibition zones of bawang dayak ethanol extract in five
various concentrations (1.25%, 2.5%, 5%, 10%, and 20%) were 7.0±1.3 mm, 8.5±0.6 mm, 9.9±0.3 mm, 11.2±0.1 mm, and 11.9±0.3 mm against P. acnes;
18.8±3.3 mm, 21.9±3.3 mm, 20.8±0.6 mm, 22.0±0.2 mm, and 23.1±0.6 mm against S. epidermidis; and 14.3±3.1 mm, 13.5±0.9 mm, 14.7±1.5 mm,
16.1±1.0 mm, and 20.1±0.6 mm against S. aureus, respectively.
Conclusion: This present study showed that bawang dayak ethanol extract was active against all the tested acne-causing bacteria. The highest
antibacterial activity was produced by 20% of bawang dayak ethanol extract against S. epidermidis.

Keywords: Antibacterial activity, Eleutherine bulbosa (Mill.) Urb., Acne, Propionibacterium acnes, Staphylococcus epidermidis, Staphylococcus aureus

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Clindamycin (positive control) 0.02 ? 31.7±0.8 27.0±0.5
0.04 ? 35.6±1.0 29.0±0.8
0.06 ? 37.1±1.6 30.4±0.4
0.08 ? 37.7±0.1 30.8±1.9
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0.2 23.0±0.4 ? ?
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?: Not tested, P. acnes: Propionibacterium acnes, S. epidermidis: Staphylococcus epidermidis, S. aureus: Staphylococcus aureus, SD: Standard deviation
Table 3: Antibacterial activity of bawang dayak ethanol extract against acne?inducing bacteria
Materials Concentration (%) Inhibition zone diameter (mm) (mean±SD; n=3)
P. acnes S. epidermidis S. aureus
Bawang Dayak ethanol extract 1.25 7.0±1.3 18.8±3.3 14.3±3.1
2.5 8.5±0.6 21.9±3.3 13.5±1.0
5 9.9±0.3 20.8±0.6 14.7±1.5
10 11.2±0.1 22.0±0.2 16.1±1.0
20 11.9±0.3 23.1±0.6 20.1±0.6
P. acnes: Propionibacterium acnes, S. epidermidis: Staphylococcus epidermidis, S. aureus: Staphylococcus aureus, SD: Standard deviation
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NOVARYATIIN, S., & ARDHANY, S. D. (2019). THE ANTIBACTERIAL ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL.) URB.) FROM CENTRAL KALIMANTAN AGAINST ACNE-CAUSING BACTERIA. International Journal of Applied Pharmaceutics, 11(5), 22-25. https://doi.org/10.22159/ijap.2019.v11s5.T0032
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