ANTIBACTERIAL ACTIVITIES OF SAPODILLA FRUIT EXTRACT INHIBITING SALMONELLA TYPHI ON MICE BALB/c

  • HASTA HANDAYANI IDRUS Departement of Microbiology, Faculty of Medicine, University Muslim Indonesia, Makassar, Indonesia, Department of Molecular Biology and Immunology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia
  • MOCHMAMMAD HATTA Department of Immunology and Microbiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.
  • AMI FEBRIZA Department of Nursing, Faculty of Sport and Health, State University of Gorontalo, Gorontalo, Indonesia.
  • VIVIEN NOVARINA A KASIM Department of Physiology, Faculty of Medicine, University of Muhammadiyah Makassar, Makassar, Indonesia.

Abstract

Objective: The aim of this study was to see the effectiveness of brown manila extract in inhibiting the growth of Salmonella typhi Thy1 bacteria in
peritoneal fluid male mice strain BALB/c.
Methods: We use manila extract which has been obtained from the extraction of the maceration method and uses the plate count agar (PCA) method
to calculate the number of colonies after conducting bacterial culture before and after the intervention.
Results: The results obtained were a significant decrease of bacterial colonies after administration of manila extract 510 mg/kgBW value p=0.009 and
extract of brown manila 750 mg/kgBB value p=0.007.
Conclusion: Giving extract of mano manila 510 mg/kgBB and 750 mg/kgBB has effectiveness in suppressing the growth of S. typhi Thy1.

Keywords: In vivo study, Sapodilla fruit extract, Salmonella typhi Thy1

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IDRUS, H. H., HATTA, M., FEBRIZA, A., & KASIM, V. N. A. (2019). ANTIBACTERIAL ACTIVITIES OF SAPODILLA FRUIT EXTRACT INHIBITING SALMONELLA TYPHI ON MICE BALB/c. International Journal of Applied Pharmaceutics, 11(5), 121-126. https://doi.org/10.22159/ijap.2019.v11s5.T0095
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