SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF CUO NANOPARTICLES

  • PARDEEP KUMAR Department of electronics science, Kurukshetra University, Kurukshetra, 136119
  • AJINKYA GIRISH NENE Applied Science Innovations Private Limited, Pune, India
  • SANDEEP PUNIA Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, India
  • MANOJ KUMAR Departemt of chemistry, Maharishi Markandeshwar University, Sadopur
  • ZAHOOR ABBAS Departemt of chemistry, Maharishi Markandeshwar University, Sadopur
  • FALAK THAKRAL Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, India
  • HARDEEP SINGH TULI Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, India

Abstract

Objective: The present study was done to see the effect of biologically synthesized CuO-NPs (Copperoxide nanoparticles) on the growth of bacterial strains.


Methods: Physico-chemical characterization of CuO-NPs was done by UV-Vis-spectrophotometer, XRD, FE-SEM, and EDS. The disc plate diffusion assay was used to evaluate the anti-bacterial effect of CuNPs.


Results: This study has shown a promising anti-bacterial activity of biosynthesized CuO-NPs at different concentrations ranging from 10 to 100 µg/ml against Escherichia coli and Staphylococcus aureus bacteria.


Conclusion: Nanoparticles (NPs) are small size particles between range 1 to 100 nm which expand their physical and chemical properties due to high surface area. The present study reveals that there may be possible utilization of biosynthesized CuO NPs for the treatment of bacterial infectious disease in near future.

Keywords: Biosynthesis, Nanoparticles, Characterization, Anti-bacterial

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KUMAR, P., NENE, A. G., PUNIA, S., KUMAR, M., ABBAS, Z., THAKRAL, F., & TULI, H. S. (2019). SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF CUO NANOPARTICLES. International Journal of Applied Pharmaceutics, 12(1), 17-20. https://doi.org/10.22159/ijap.2020v12i1.36271
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