• ILYA GULYAKIN Sechenov University, 8/2 Trubeckaya Str., Moscow, 119991, Russia



scar tissue (scar), keloid scars (keloids), pathological scarring, scar treatment methods, transdermal therapeutic systems


Modern medicine has achieved significant results in the development of techniques to avoid surgeries. However, surgical methods are still one of the main tools for treating pathologies in the human body. Plastic surgery and cosmetology are gaining popularity every year, and sports injuries require the use of combined treatment methods, but any such intervention leads to the risk of keloids. The younger the person, the higher the likelihood of developing a keloid, due to the high degree of elasticity of the skin at an earlier age, which is prone to scarring than in older people. Women are at higher risk of developing keloids than men because their skin is more elastic. Thus, children and young women are most at risk of keloid formation, both as a result of physiological processes of skin scarring and preference for plastic surgery, cosmetic procedures and other methods of correction. In world pharmaceutical practice, there are not enough existing ways to prevent the development of keloid. It is necessary to conduct research on the selection of a fundamentally new structural basis for a transdermal therapeutic system containing the most effective and safe compounds of the regenerating and antioxidant mechanisms of action (vitamins and other biologically active compounds) from the point of view of preventing the formation of keloids, which will help in solving the problem of not only preventing the formation of keloids in dermis, but also its subsequent growth and exit to the surface layers of the skin.


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