• INSAN SUNAN KURNIAWANSYAH Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, Indonesia
  • IYAN SOPYAN PUSDI Drug Delivery and Drug Disposition Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, Indonesia
  • GENI REFSI Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, Indonesia



rheology, organoleptic, pH, clarity, gelling capacity, in situ gel, ophthalmic.


In situ ophthalmic gel is a type of eye drug preparation that has a higher bioavailability value and has a longer contact time with maximum therapeutic effect and with minimal side effects compared to conventional eye preparations. The preparation of ophthalmic in situ gel is required characterization to make sure that the prepared preparations meet the standards and are safe when used. This journal review aims to look at the methods used in characterizing physical properties in in situ ophthalmic gel formulations with different active substances such as rheology studies, organoleptic tests, pH, clarity, and gelling capacity. In order to get the best formulation of in situ ophthalmic gel preparations so as to provide maximum therapeutic effect.


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How to Cite

KURNIAWANSYAH, I. S., SOPYAN, I., & REFSI, G. (2022). PHYSICAL CHARACTERIZATION OF IN SITU OPHTHALMIC GEL: A CONCISE REVIEW. International Journal of Applied Pharmaceutics, 14(1), 18–21.



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