COMPARATIVE STUDY OF THE SHIVA GUGGULU AND SIMHANADA GUGGULU IN THE MANAGEMENT OF AMAVATA (RHEUMATOID ARTHRITIS)


Manoj Kumar Gupta, Arun Kumar Shrivastava, Ajit Pal Singh Chauhan, Dinesh Singh Gaur, Krisna Kumar Mishra, Shrikrishna Sharma

Abstract


Objective: Comparison of effectiveness of two drugs (Shiva Guggulu and Simhanada Guggulu in the same dose of both drug given separately in two different groupA and Group B) on patients of Amavata.

Methods: Patients between 18-60 y of age with classical features of Amavata [9] from OPD and IPD of Government autonomous Ayurvedic College and Hospital were selected for the present work; irrespective of their sex, religion, education, etc. Detailed research Performa was prepared to incorporate all the signs and symptoms of the disease Amavata is the second most common joint disorders. Nowadays erroneous dietary habits, lifestyle and environment have led to various autoimmune disorders i.e. Amavisajanya Vikaara and Amavata is one among them. Rheumatoid arthritis can be correlated with Amavata in view of its clinical features. Many research studies have been done to solve this clinical enigma, but an effective, safe, less complicated treatment is still required for the management of Amavata. In the present study, 24 patients of Amavata were registered and randomly grouped into two. In group A, Shiva Guggulu 6 g/day in divided doses and in group B, Simhanada Guggulu 6 g/day in divided doses were given for 8 w. On analysis of the results, it was found that Simhanada Guggulu provided better results as compared to Shiva Guggulu in the management of Amavata. In group A, the mean score of grip strength was 1.14 before treatment, which was reduced to 0.57 after treatment, with 50% relief. It was statistically insignificant. The mean score of grip strength in group B was 2.4 before treatment, which was reduced to 1.5 after treatment, with 37.5% relief. It was statistically highly significant.

Results: Before treatment the mean score of walking time in group A was 2, which was reduced to 1 after treatment, with 50% relief. It was statistically insignificant. The mean score of walking time in group B was 1.75 before treatment, which was reduced to 0.75 after treatment, with 45.71% relief. It was statistically significant.

In group A, the mean score of foot pressure was 1 before treatment, which was decreased to 0.66 after treatment, with 33.33% relief. It was statistically insignificant. The mean score of foot pressure in group B was 2.3 before treatment, which was decreased to 1.4 after treatment with, 39.13% relief. It was statistically highly significant.

In group A, the mean score of general functional capacity was 1.33 before treatment, which was reduced to 0.66 after treatment, with 50% relief. It was statistically highly significant. The mean score of general functional capacity in group B was 1.66 before treatment, which was reduced to 0.66 after treatment, with 60% relief and was statistically insignificant.

In group A, the mean score of the degree of disease activity was 1.75 before treatment, which was reduced to 1 after treatment, with 42.85% relief. It was statistically highly significant. The mean score of the degree of disease activity in group B was 1.5 before treatment, which was reduced to 0.75 after treatment, with 50% relief. It was statistically significant.

Regarding ESR value, the mean scores before treatment in A and B groups were 54.5 and 55.2, respectively, and they were reduced to 45.3 and 40.1, respectively, after treatment. Group A percentage relief was 16.88%, while in group B it was 27.35%.

An apparent difference in improvement of all the cardinal symptoms was observed with the treatment. On comparing Group B proved to be better than Group A. Statistically highly significant difference was found in the improvement of Sandhigraha and statistically significant difference was found in the improvement of Sandhishoola and Sparshasahyata by Simhanada Guggulu than Shiva Guggulu, whereas insignificant difference was observed in the improvement of Sandhishotha. So, from the obtained data it may be inferred that group B is more effective than groupA.

Conclusion: It was observed from the treatment that Simhanada Guggulu provided comparatively better relief in cardinal signs and symptoms of Amavata.

Keywords: Agni, Ama, Amavata, Rheumatoid arthritis, Shiva Guggulu, Simhanada Guggulu


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About this article

Title

COMPARATIVE STUDY OF THE SHIVA GUGGULU AND SIMHANADA GUGGULU IN THE MANAGEMENT OF AMAVATA (RHEUMATOID ARTHRITIS)

Date

04-04-2016

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Journal

International Journal of Applied Pharmaceutics
Vol 8, Issue 2, 2016 Page: 5-12

Online ISSN

0975-7058

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129 Views | 33 Downloads

Authors & Affiliations

Manoj Kumar Gupta
Department of Roga and Vikriti Vijnana Government Ayurvedic College and Hospital, Atarra, Banda, Uttarpradesh, India,
India

Arun Kumar Shrivastava
Department of Sharir Kriya vijnana, Government Ayurvedic College and Hospital, Atarra, Banda, Uttarpradesh, India

Ajit Pal Singh Chauhan
Department of Sharir Kriya Vijnana, Government Ashtang Ayurvedic College and Hospital, Lokmanya Nagar, Indore, Madhyapradesh, India

Dinesh Singh Gaur
Department of Shalakya, Government Ashtang Ayurvedic College and Hospital, Lokmanya Nagar, Indore, Madhyapradesh, India

Krisna Kumar Mishra
Department of Sharir Kriya Vijnana,Government Ayurvedic College and Hospital, Atarra, Banda, Uttarpradesh, India India

Shrikrishna Sharma
Department of Roga and Vikriti Vijnana, National Institute of Ayurveda, Jaipur, Rajasthan, India


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