@article{BELATRIX_PUSPITAWATI_DJAIS_2019, title={EFFECT OF JAVANESE TURMERIC ETHANOL EXTRACT ON THE ERADICATION OF CANDIDA ALBICANS BIOFILMS IN EARLY, INTERMEDIATE, AND MATURATION PHASES}, volume={11}, url={https://journals.innovareacademics.in/index.php/ijap/article/view/33308}, DOI={10.22159/ijap.2019.v11s1.148}, abstractNote={<p><strong>Objectives</strong>: The aim of this research was to observe the effect of Javanese turmeric ethanol extract (JTEE) on the eradication of Candida albicans in<br>various phases of biofilm development.<br><strong>Methods</strong>: C. albicans biofilms were exposed to JTEE at a concentration 1–45% for 1 h. Cell viability was tested by 3-(4,5-dimethylthiazol-2-yl)-2,5-<br>diphenyltetrazolium bromide assay, and the wavelength was read at 570 nm.<br><strong>Results</strong>: The results showed that the 50% minimal biofilm eradication concentration was 30% in the early phase, 20% in the intermediate phase, and<br>25% in the maturation phase of the biofilm. The eradication percentage increased along with increasing JTEE concentration, but decreased with the<br>age of the biofilm.<br><strong>Conclusion</strong>: We concluded that JTEE has the potential to eradicate C. albicans biofilms in various phases of development.<br><br></p>}, number={1}, journal={International Journal of Applied Pharmaceutics}, author={BELATRIX, BETA and PUSPITAWATI, RIA and DJAIS, ARIADNA ADISATTYA}, year={2019}, month={Apr.}, pages={1–4} }