TY - JOUR AU - YANUAR, REZON AU - SUNIARTI, DEWI FATMA AU - DJOHAN, WIDURINI PY - 2019/04/05 Y2 - 2024/03/29 TI - EFFICACY OF JAVANESE TURMERIC ETHANOL EXTRACT IN ERADICATING STREPTOCOCCUS SANGUINIS AND PORPHYROMONAS GINGIVALIS BIOFILM JF - International Journal of Applied Pharmaceutics JA - Int J App Pharm VL - 11 IS - 1 SE - Original Article(s) DO - 10.22159/ijap.2019.v11s1.155 UR - https://journals.innovareacademics.in/index.php/ijap/article/view/33321 SP - 18-22 AB - <p><strong>Objective</strong>: Javanese turmeric is an Indonesian native medicinal plant with antibacterial activities. This study aimed to analyze the efficacy of identified<br>Javanese turmeric ethanol extract (IJTEE) in eradicating Streptococcus sanguinis and Porphyromonas gingivalis biofilms.<br><strong>Methods</strong>: Biofilm assay: Single and combination biofilms formed at different phases were exposed to IJTEE in 0.5–25% concentrations for 1 h. The<br>percentage of eradication was tested using the microtetrazolium assay.<br><strong>Results</strong>: The efficacy of IJTEE in eradicating the biofilm was equal to that of chlorhexidine against the early phase of biofilm formation. IJTEE is more<br>effective against S. sanguinis biofilm formation than against P. gingivalis biofilm formation.<br><strong>Conclusion</strong>: IJTEE can eradicate S. sanguinis and P. gingivalis biofilms.</p> ER -