A BRIEF REVIEW ON PROCESS ANALYTICAL TECHNOLOGY (PAT)


Akash S. Mali, Monali Jagtap, P Karekar, A MaruŠka

Abstract


Process analytical technology (PAT) has been defined as a mechanism to design, analyze and control pharmaceutical manufacturing processes through measurement of critical process parameters which affect critical quality attributes. PAT checks the quality of raw material attributes both physically and chemically (i.e. at off-line, on-line, in-line). PAT involves a shift from testing the quality of building to the quality of products by testing at several intermediate steps. PAT saves a huge amount of time and money required for sampling and analysis of products. The main goal of PAT is to provide successful tools such as multivariate data analysis and acquisition tools, modern process analyzers or analytical chemistry, endpoint process monitoring, controlling tools and continuous improvement and knowledge improvement tools. In this review attempt has been carried out to explore the concept of PAT, different tools of PAT, goals of PAT, How it Works and Its benefits.

Keywords: PAT, Pharmaceutical, Manufacturing process, Quality assurance.

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References


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About this article

Title

A BRIEF REVIEW ON PROCESS ANALYTICAL TECHNOLOGY (PAT)

Date

07-01-2016

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 8, Issue 1, 2016 Page: 10-15

Online ISSN

0975-7066

Statistics

284 Views | 192 Downloads

Authors & Affiliations

Akash S. Mali
Vytautas Magnus University, Lithuania

Monali Jagtap
Vytautas Magnus University, Lithuania

P Karekar
Department of Pharmacy (GIPER) Shivaji University Kolhapur Maharashtra India

A MaruŠka
Centaur Pharmaceuticals Pvt. Ltd. Pune, India


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