USE OF ION ASSOCIATION COMPLEX FORMATION FOR THE SPECTROPHOTOMETRIC DETERMINATION OF ITOPRIDE HCL IN BULK AND ITS PHARMACEUTICAL PREPARATIONS


P. V. Lakshmana Rao, C. Rambabu

Abstract


Objective: The authors report two simple, accurate and economic spectrophotometric methods A and B for the determination of Itopride hydrochloride in bulk and dosage forms.

Methods: The proposed methods are based on the formation of chloroform soluble ion-associates in the presence of acidic dyes namely BPB (Method A) and BCP (Method B) exhibiting lmax at 418 and 418 nm respectively.

Results: Beer’s law is found to be obeyed in the concentration range of 2.0-10.0 µg/ml and 2.0-10.0 µg/ml. The molar absorptivities are found to be 1.42x104 and 9.61x103L/mol. cm for methods A and B. These methods are successfully applied for the assay of Itopride hydrochloride in pharmaceutical formulations.


Keywords


Itopride hydrochloride, BPB, BCP, Spectrophotometry

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About this article

Title

USE OF ION ASSOCIATION COMPLEX FORMATION FOR THE SPECTROPHOTOMETRIC DETERMINATION OF ITOPRIDE HCL IN BULK AND ITS PHARMACEUTICAL PREPARATIONS

Keywords

Itopride hydrochloride, BPB, BCP, Spectrophotometry

DOI

10.22159/ijcpr.2017v9i1.16620

Date

31-12-2016

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 1, 2017 Page: 81-84

Online ISSN

0975-7066

Statistics

35 Views | 43 Downloads

Authors & Affiliations

P. V. Lakshmana Rao

C. Rambabu


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