ADAPTOGENIC ACTIVE COMPONENT FROM MYXOPYRUM SMILACIFOLIUM

  • E. N. Siju Department of Pharmacology, Academy of Pharmaceutical Science, Pariyaram Medical College, Kannur 670503, Kerala, India
  • Jolly Samu Department of Pharmacology, Academy of Pharmaceutical Science, Pariyaram Medical College, Kannur 670503, Kerala, India
  • M. Minil Department of Pharmacology, Academy of Pharmaceutical Science, Pariyaram Medical College, Kannur 670503, Kerala, India
  • G. R. Rajalakshmi College of Pharmaceutical Sciences, Government Medical College, Kozhikode 673008, Kerala, India

Abstract

Objective: The present study was designed to investigate the adaptogenic active component from the extracts of Myxopyrum smilacifolium.

Methods: The plant extract was undergone different separation technique viz precloumn, HPTLC, etc for isolation of pure compound. Thereafter the pure compound was subjected to IR, NMR, LC-MS for structural elucidation.

Results: Chemical characterization of the adaptogenic fraction by spectroscopy showed iridoid glycoside as major constituents.

Conclusion: The present study showed iridoid glycoside is considered the adaptogenic agents of Myxopyrum smilacifolium Blume.

Keywords: Myxopyrum smilacifolium, HPTLC, LCMS, NMR, FTIR

References

1. Evan WC. Trease and Evans Pharmacognosy. 14th ed. India: Harcourt Brace and company; 1998. p. 138-46, 194.
2. Savithramma N, Linga Rao M. Phytochemical screening of Thespesia populnea Sol. and Tridax procumbens L. J Chem Pharm Res 2011;3 Suppl 5:28-34.
3. Varier PS. Indian medical plants: a compendium of 500 species. Vol. 4. Madras: Orient Longman Limited; 1995. p. 98.
4. Sundharmini D, Ashalatha S Nair. Antimicrobial activity of triterpenoid fractions from Myxopyrum smilacifolium blume. Ethnobotanical Leaflets 2008;12:912-5.
5. Gopalakrishnan S, Rajameena R. Wound healing activity of the Ethanol extract of the leaves of Myxopyrum serratulum A. W. Hill in Rats. Int J Pharm Sci Rev 2013;22 Suppl 1:143-7.
6. Trim, Hill, Weiffering JH. Accubinating glucoside (Psuedoinikane) and verwandle heteroside Ale. systematische. Phytochemistry; 1998. p. 103-4.
7. Melanie Alfred. A Reference book for the biological activity of the constituents of Morinda citrifolia, 2ed. Australia: M and R Naturopathic Clinic; 2012. p. 18-20.
8. Provo, Utah. International Iridoid Research Symposium. International Iridoid Research Council; 2010. p. 3-6.
9. Biren NS, Pankaj B Patel, Ankit BP, Dikshit CM. Rehmannia glutinosa-A Phyto-pharmacological review. Pharmacol Online 2010;1:737-53.
Statistics
180 Views | 1062 Downloads
How to Cite
Siju, E. N., J. Samu, M. Minil, and G. R. Rajalakshmi. “ADAPTOGENIC ACTIVE COMPONENT FROM MYXOPYRUM SMILACIFOLIUM”. International Journal of Current Pharmaceutical Research, Vol. 9, no. 1, Dec. 2016, pp. 110-3, doi:10.22159/ijcpr.2017v9i1.16630.
Section
Original Article(s)