NANOSUSPENSION: AN OVERVIEW


Smita S. Aher, Sagar T. Malsane, R. B. Saudagar

Abstract


Nanosuspensions are important carriers to develop novel drug formulations. Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Nanosuspension technology solved the problem of drugs which are poorly aqueous soluble and less bioavailability. Stability and bioavailability of the drugs can be improved by the Nanosuspension technology. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions. Nanosuspensions can be delivered by oral, parenteral, pulmonary and ocular routes. Nanosuspensions can also be used for targeted drug delivery when incorporated in theOcular inserts and mucoadhesive hydrogels. Currently, efforts are being directed to extending their applications in site-specific drug delivery.


Keywords


Nanosuspension, Solubility enhancement, Particle size, Surfactant, Colloidal dispersion, Oral bioavailability

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About this article

Title

NANOSUSPENSION: AN OVERVIEW

Keywords

Nanosuspension, Solubility enhancement, Particle size, Surfactant, Colloidal dispersion, Oral bioavailability

DOI

10.22159/ijcpr.2017.v9i3.19584

Date

05-05-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 3, 2017 Page: 19-23

Online ISSN

0975-7066

Statistics

147 Views | 839 Downloads

Authors & Affiliations

Smita S. Aher
Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India

Sagar T. Malsane
Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India

R. B. Saudagar
Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India


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