GC-MS ANALYSIS OF METHANOLIC STEM EXTRACT OF GYNOCHTHODES RIDSDALEI, RAZAFIM AND B. BREMER, AN ENDEMIC, ENDANGERED MEDICINAL PLANT OF SOUTHERN WESTERN GHATS


Renji R. Nair, A. Gangaprasad

Abstract


Objective: The present research study was undertaken to determine the presence of bioactive components present in the methanolic stem extract of Gynochthodes ridsdalei using Gas Chromatography–Mass Spectrometry (GC-MS) analysis.

Methods: the Fresh stem of Gynochthodes ridsdalei collected from the forest areas of Ponmudi region of Thiruvananthapuram district of Kerala state, India was used. The mass spectrum GC-MS of the crude methanolic extract was estimated using the database of National Institute of Standard and Technology (NIST).

Results: The active principles with their retention time, peak area, molecular formula, molecular weight, structure and category of the compound were predicted. The analysis revealed the presence of 52 bioactive components. Most of the identified compounds are basically biological important. The components were identified by comparing their retention time and peak area with that of literature and by interpretation of mass spectra. The phyto components screened were of biological importance. Some of them were sterols, anthraquinones, vitamins etc

Conclusion: The result reveals the existence of various bioactive compounds and validates the earlier reports of therapeutic importance of the plant. Gynochthodes ridsdalei is recommended as a plant of phytochemical and pharmaceutical importance


Keywords


Gynochthodes ridsdalei, Morinda reticulata, endangered, southern Western Ghats, gas chromatography

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References


Dutt R, Garg V, Madan AK. Can plants growing in diverse hostile environments provide a vital source of anticancer drugs? J Cancer Ther 2014;10:13-37.

Mohanan N, Sivadasan M. Flora of Agasthyamala, Bishen Singh Mahendra Pal Singh. Dehradun; 2002. p. 333.

Zhang A, Sun H, Wang X. Recent advances in natural products from plants for treatment of liver diseases. Eur J Med Chem 2013;63:570-57.

Han YS, van der Heijden R, Verpoorte R. Biosynthesis of anthraquinone in cell cultures of the Rubiaceae. Plant Cell Tissue Organ Culture 2001;67:201–20.

Santos CC, Salvadori MS, Mota VG, Costa LM, de Almeida AA, de Oliveira GA, et al. Antinociceptive and antioxidant activities of phytol in vivo and in-vitro models. Neurosci J 2013;11. http://dx.doi.org/10.1155/2013/949452

Gamble JS. Flora of Presidency of Madras. Vol II. Bishen Singh Mahendra Pal Singh, Dehradun; 1921. p. 650-2.

Ijinu TP, Anish N, Shiju H, George V, Pushpangadan P. Home gardens for nutritional and primary health security of rural poor of South Kerala. Indian J Traditional Knowledge 2011;10:413-28.

Razafimandimbison SG, Bremer B. Nomenclatural changes and taxonomic notes in the tribe Morindeae (Rubiaceae). Adansonia 2011;33:283-309.

Sharma MD, Rautela I, Gahlot M, Sharma N, Koshy EP. GC–MS analysis of photo components in juice sample of Indian cane: Saccharum barberi. Int J Pharm Sci Res 2015;6:5147-53.

Stein SE. National Institute of Standards and Technology (NIST), Mass Spectral Database and Software. Version 3.02. Gaithersburg, USA; 1990.

Mohammad TG, Mohammed HE, Ali J, Seyedhossein H, Mohammad M. Antimicrobial activity, toxicity and stability of phytol as a novel surface disinfectant. Environ Health Eng Manage J 2015;2:13-6.

Peter O, Malin H, Lars I Hellgren, Rikard H. Phytol: a chlorophyll component with anti-inflammatory and metabolic properties. Recent Advances in Redox-Active Plant and Microbial Products; 2014. p. 345-59.

Netscher T. Synthesis of vitamin E. Vitamins Hormones 2007;76:155-202.

Rao CV, Newmark HL, Reddy BS. Chemopreventive effect of squalene on colon cancer. Carcinogens 1998;19:287-97.

. Mohan VR, Sudha T, Chidambarampillai S. GC-MS analysis of bioactive components of aerial parts of Kirganelia Reticulata poir (Euphorbiaceae). J Curr Chem Pharm Sci 2013;3:4.

Alagammal M, Tresina P, Sand Mohan VR. GC-MS determination of bioactive components of Polygala javana dc. Int J Curr Pharm Res 2012;4:42-4.




About this article

Title

GC-MS ANALYSIS OF METHANOLIC STEM EXTRACT OF GYNOCHTHODES RIDSDALEI, RAZAFIM AND B. BREMER, AN ENDEMIC, ENDANGERED MEDICINAL PLANT OF SOUTHERN WESTERN GHATS

Keywords

Gynochthodes ridsdalei, Morinda reticulata, endangered, southern Western Ghats, gas chromatography

DOI

10.22159/ijcpr.2017.v9i3.19665

Date

05-05-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 3, 2017 Page: 98-101

Online ISSN

0975-7066

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27 Views | 18 Downloads

Authors & Affiliations

Renji R. Nair
Plant Tissue Culture and Molecular Biology Lab, Department of Botany, University of Kerala, Thiruvananthapuram, Kerala, India, 695581

A. Gangaprasad
Plant Tissue Culture and Molecular Biology Lab, Department of Botany, University of Kerala, Thiruvananthapuram, Kerala, India, 695581


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