MUCOADHESIVE BUCCAL DRUG DELIVERY SYSTEM: REVIEW ARTICLE


Monali Sonawane, Dattatrey Shinkar, Ravindrasaudagar .

Abstract


The advantage of buccal drug delivery system over the conventional and systemic formulation majority. It helps enhance the bioavailability through bypassing the first-pass metabolism effect. The mucosal surface better absorption and prolong resident time. Bioadhesion can be defined as the phenomenon of interfacial molecular attractive force in midst of the surface of the biological substrate and the natural or synthetic polymers, which allows the polymers to adher to the biological surface for an extended period of time. Among the various transmucosal sites available, mucosa of the buccal cavity was found to be the most convenient and easily approachable site for the delivery of the therapeutic agent for both local and systemic delivery. This review also covers available marketed product as buccal drug delivery system and future aspects of buccal drug delivery system.


Keywords


Buccal drug delivey system, Anatomy and Physiology, Bioadhesion, Transmucosal dosage forms, Evaluation parameters

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About this article

Title

MUCOADHESIVE BUCCAL DRUG DELIVERY SYSTEM: REVIEW ARTICLE

Keywords

Buccal drug delivey system, Anatomy and Physiology, Bioadhesion, Transmucosal dosage forms, Evaluation parameters

DOI

10.22159/ijcpr.2017v9i4.20960

Date

14-07-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 4, 2017 Page: 1-4

Online ISSN

0975-7066

Statistics

133 Views | 121 Downloads

Authors & Affiliations

Monali Sonawane
Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India

Dattatrey Shinkar
Department of Quality Assurance, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India
India

Ravindrasaudagar .
3Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India
India


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