IN VITRO ANTI-DIABETIC ACTIVITY OF MICROENCAPSULATED AND NON-ENCAPSULATED ASTAXANTHIN


V. Suganya, V. Anuradha, M. Syed Ali, P. Sangeetha, P. Bhuvana

Abstract


Objective: Diabetes is a long term condition which indicates the high blood pressure. The symptoms indicates, polyuria (frequent urination), they will become increasingly thirsty (polydipsia) and hungry (polyphagia). Many drugs has been discovered for curing diabetes. Recent studies reported that the administration of astaxanthin reduces the blood pressure in the diabetic patient. Astaxanthin is a powerful antioxidant found in wide variety of aquatic living organism which has wide applications in pharmacological studies.

Methods: In vitro antidiabetic study of both encapsulated and non-encapsulated astaxanthin such as DNSA method, starch-iodine color assay method and α glycosidase enzymes assay was carried out.

Results: The results of the present study indicated that both encapsulated and non-encapsulated astaxanthin shows higher antidiabetic activity in all the method. Each test samples possess the best activity when compared to standard drug acarbose.

Conclusion: The present study, it is concluded that both non-encapsulated and encapsulated astaxanthin exhibit good antidiabetic activity.


Keywords


Astaxanthin, Anti-diabetic, DNSA, Starch-iodine, Acarbose, α glycosidase

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About this article

Title

IN VITRO ANTI-DIABETIC ACTIVITY OF MICROENCAPSULATED AND NON-ENCAPSULATED ASTAXANTHIN

Keywords

Astaxanthin, Anti-diabetic, DNSA, Starch-iodine, Acarbose, α glycosidase

DOI

10.22159/ijcpr.2017v9i5.22147

Date

21-09-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 5 (Aug-Sep), 2017 Page: 90-96

Online ISSN

0975-7066

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Authors & Affiliations

V. Suganya
Department of Biochemistry, Mohamed Sathak College of arts and Science, Sholinganallur, Chennai, Tamil Nadu, India
India

V. Anuradha
Department of Biochemistry, Mohamed Sathak College of arts and Science, Sholinganallur, Chennai, Tamil Nadu, India
India

M. Syed Ali
Department of Biochemistry, Mohamed Sathak College of arts and Science, Sholinganallur, Chennai, Tamil Nadu, India
India

P. Sangeetha
Department of Biochemistry, Mohamed Sathak College of arts and Science, Sholinganallur, Chennai, Tamil Nadu, India
India

P. Bhuvana
Department of Biochemistry, Mohamed Sathak College of arts and Science, Sholinganallur, Chennai, Tamil Nadu, India
India


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