ANTITUSSIVE ACTIVITY ASSAYOF SAGE (LANTANA CAMARA L.)LEAVES BASED ON THE BREATHING PATTERN OF MALE GUINEA PIGS USING ADOBE AUDITION 1.5 PROGRAM


Wa Ode Yuliastri, Andreanus Soemardji, Mus Ifaya

Abstract


Objective: The present study was aimed to assay antitussive activity of Sage (Lantana camara L.)leaves

Methods: Antitussive Assay was conducted based on The Breathing Pattern of Male Guinea Pigs Using Adobe Audition 1.5 Program.

Results: Comparison of the frequency of breathing patterns guinea pig groups sage (Lantana camara L.)  leaves water fraction at a dose of 4.58 mg/kg bw dose of 9.17 mg/kg bw and doses of 18.35 mg/kg bw statistically significantly different results (p<0.05), as well as the ratio of intensity of the breathing pattern of the guinea pig. As for the water extract, significant differences in the frequency comparison guinea pig respiratory pattern is only shown at a dose of 18.35 mg/kg bw on the other side for its intensity did not show significant differences (p<0.05).

Conclusion: Ethanol extract of sage leaves in the form of three fractionation (ethyl acetate, n-hexane, and water) can improve the breathing pattern guinea pig cough, especially at a dose of 18.35 mg/kg bw.

 


Keywords


Antitussive activity, Sage (Lantana camara L.)leaves, The frequency of breathing pattern, The breathing pattern

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About this article

Title

ANTITUSSIVE ACTIVITY ASSAYOF SAGE (LANTANA CAMARA L.)LEAVES BASED ON THE BREATHING PATTERN OF MALE GUINEA PIGS USING ADOBE AUDITION 1.5 PROGRAM

Keywords

Antitussive activity, Sage (Lantana camara L.)leaves, The frequency of breathing pattern, The breathing pattern

DOI

10.22159/ijcpr.2017v9i5.22154

Date

21-09-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 5 (Aug-Sep), 2017 Page: 124-127

Online ISSN

0975-7066

Statistics

72 Views | 21 Downloads

Authors & Affiliations

Wa Ode Yuliastri
1Department of Pharmachy, STIKES Mandala Waluya, Kendari, Indonesia
Indonesia

Andreanus Soemardji
Pharmacology Clinical Pharmachy Research Group, School of Pharmachy, Bandung Institute of Technology, Bandung, Indonesia
Indonesia

Mus Ifaya
Department of Pharmachy, STIKES Mandala Waluya, Kendari, Indonesia
Indonesia


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