PHARMACOLOGICAL EVALUATION OF ANTIANXIETY ACTIVITY OF DESMOSTACHYA BIPINNATA LEAVES IN ANIMAL MODELS


Veena Rani I., Kiranmai G., Ravi Pratap Pulla

Abstract


Objective: Anxiety is a widespread psychiatric disorder affecting around 5% of the population. Furthermore, it is difficult to predict patient’s response to any given treatment. In the traditional systems of medicine, many plants have been used to treat anxiety and depression for thousands of years. Desmostachyabipinnata belongs to the family Poaceae, have pharmacological actions like dysentery and menorrhagia, and as a diuretic. The present study was designed to evaluate the antianxiety activity of the alcoholic and aqueous extracts of Desmostachyabipinnata leaves in rodents.

Methods: Antianxiety activity was screened by different methods like elevated plus maze model and actophotometer.

Results: The results infer that reduced aversion fear elicits anti-anxiety activity.

Conclusion: It was concluded that alcoholic and aqueous extracts of Desmostachyabipinnata leaves are having anti-anxiety activity among which alcoholic extract of Desmostachyabipinnata leaves showing more significant activity over the aqueous extract.

 


Keywords


Desmostachyabipinnata, Antianxiety activity, Elevated plus maze, Actophotometer

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About this article

Title

PHARMACOLOGICAL EVALUATION OF ANTIANXIETY ACTIVITY OF DESMOSTACHYA BIPINNATA LEAVES IN ANIMAL MODELS

Keywords

Desmostachyabipinnata, Antianxiety activity, Elevated plus maze, Actophotometer

DOI

10.22159/ijcpr.2017v9i5.22159

Date

21-09-2017

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 9, Issue 5 (Aug-Sep), 2017 Page: 152-154

Online ISSN

0975-7066

Statistics

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Authors & Affiliations

Veena Rani I.
India

Kiranmai G.
1Department of Pharmacology, SSJ College of Pharmacy, Vattinagulapally, Hyderabad-75
India

Ravi Pratap Pulla
1Department of Pharmacology, SSJ College of Pharmacy, Vattinagulapally, Hyderabad-75
India


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