PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF MILLINGTONIA HORTENSIS (L)

Authors

  • Janaki A. Department of Zoology, Presidency College (Autonomous), Chennai-05, Tamilnadu, India
  • Kaleena P. K. Department of Zoology, Presidency College (Autonomous), Chennai-05, Tamilnadu, India
  • Elumalai D. Department of Zoology, Presidency College (Autonomous), Chennai-05, Tamilnadu, India
  • Hemalatha P. Department of Zoology, Presidency College (Autonomous), Chennai-05, Tamilnadu, India
  • Babu M. Department of Zoology, Presidency College (Autonomous), Chennai-05, Tamilnadu, India
  • Velu K. Department of Zoology, Presidency College (Autonomous), Chennai-05, Tamilnadu, India
  • Sudha Ravi Department of Zoology, Presidency College (Autonomous), Chennai-05, Tamilnadu, India

DOI:

https://doi.org/10.22159/ijcpr.2017v9i5.2217

Keywords:

Millingtonia hortensis, Phyto compounds, Antioxidant activity, GC-MS analysis, Anti bacterial activity

Abstract

Objective: Millingtonia hortensis Linn (Bignoniaceae) is commonly known as cork tree and Akash neem. Aim of studies to determine the antioxidant activity and antibacterial activity.

Methods: The antioxidant activity of different solvent extracts were measured by chemical analyses involving the assay of 1,1-diphenyl-2-picryhydrazyl (DPPH) radical scavenging activity and super oxide radical scavenging activity.

Results: Phytochemicals (secondary metabolites) screening of methanol, chloroform, ethanol, petroleum ether, aqueous leaf extracts revealed the presence of carbohydrates, tannins, saponins, flavonoids, alkaloids, betacyanins, phenols and coumarins.

Conclusion: The presence of these phytochemicals and antioxidant capacity support the use of this plant as an antibacterial agent against the group of micro organisms tested.

 

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References

Maher G, Enas A, Hanee A, Maisa A, Jafar E, Ismael O. Antimicrobial activity of crude extracts of some plant leaves. Res J Microbiol 2012;7:1-10.

Kabra AO, Bairagi GB, Mahamuni AS, Wanare RS. In vitro antimicrobial activity and phytochemical analysis of the peels of Citrus medica L. Int J Res Pharm Biomed Sci 2012;3:34-7.

Krishna Raju AV, Rao TVN, Sundararaju D. Assessment of bioactivity of Indian medicinal plants using brine shrimp (Artemia salina) lethality. Int J Appl Sci Eng 2005;2:125-34.

Chanda S, Dave R. In vitro models for antioxidant activity evaluation and some medicinal plants possessing antioxidant properties: an overview. Afr J Microbiol 2009;3:981-96.

Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ. Reversals of age-related declines in neuronal signal transduction congnitive and motor behavioural deficits with blueberry, spinach or strawberry dietary supplementation. J Neurol Sci 1999;19:8114-21.

Gordon MH, Weng XC. Antioxidants properties of extracts from Tanshen (Salvia militiorrhiza Bunge). Food Chem 1992;44:119-22.

Gu LW, Weng XC. Antioxidant activity and components of Salvia plebeian R, Br-a chineses herb. Food Chem 2001;73:299-305.

Pyo YH, Lee TC, Logendrac H, Rosen RT. Antioxidant activity and phenolic compounds of Swiss Chard (Beta vulgaris subspecies cycla) extracts. Food Chem 2004;85:19-26.

Branen AL. Toxicology and biochemistry of butylated hydroxyl anisole and butylated hydroxyl toluene. J Am Oil Chem Soc 1975;52:59-63.

Grice HC. Safety evaluation of butylated hydroxyl toluene (BHT) in the liver, lung and gastro intestinal tract. Food Chem Toxicol 1986;24:1127-30.

Wichi HP. Enhanced tumor development by butylated hydroxyl anisole (BHA) from the perspective of effect on forestomach and oesophageal squamous epithelium. Food Chem Toxicol 1988;26:717-23.

Rice-Evans C. Flavonoids and isoflavones: absorption metabolism and bioactivity. Free Rad Biol Med 2004;36:827-8.

Chanda S, Rakholiya K. Combination therapy: synergism between natural plant extracts and antibiotics against infectious diseases. Microbiol Book Series; 2011. p. 520-9.

Harishchandra MR, Rajan PR, Singh Satyendrakumar RP. Study of krimighna effect of nimba (Azadiracta indica A. Juss.) Patra as rakshoghna dhoopan by culture and sensitivity method W. S. R. to pyogenic bacteria. Int Res J Pharm 2012;3:142-6.

Silva MSP, Brandao DO, Chaves TP, Filho ALNF, Costa EMDB, Santos VL. Study bioprospecting of medicinal plant extracts of the semiarid Northeast: contribution to the control of oral microorganisms. J Evidence-Based Complementary Altern Med 2012;1-6. http://dx.doi.org/10.1155/2012/681207

Tansuwanwong S, Yamamoto H, Imai K, Vinitketkumnuen U. Antiproliferation and apoptosis on RKO colon cancer by Millingtonia hortensis. Plants Foods Hum Nutr 2009;64:11-7.

Sharma M, Puri S, Sharma PD. Antifungal activity of Millingtonia hortensis, Indian J Pharm Sci 2007;69:599-601.

Harbourne JB. Phytochemical methods. Chapman and Hall, London; 1998. p. 6.

Blois MS. Antioxidant determinations by the use of a stable free radical. Nature 1958;181:1199-200.

Nuno Rainha, Elisabete Lima, Jose Baptista, Carolina Rodrigues. Antioxidant properties, total phenolic, total carotenoid and chlorophyll content of anatomical parts of Hypericum foliosum. J Med Plants Res 2011;5:1930-40.

Lesueur D, de Rocca Serra D, Bighelli A, Hoi TM, Ban NK, Thai TH, et al. Chemical composition and antibacterial activity of essential oil of Michelia faveolata meryll ex dandy from vietnam. Flavour Fragr J 2007;22:317-21.

Fadila Moussaoui, Tajelmolk Alaoui. Evaluation of antibacterial activity and synergistic effect between antibiotic and the essential oils of some medicinal plants. Asian Pac J Trop Biomed 2016;6:32–7.

Choi YM, Noh DO, Cho SY, Suh HJ, Kim KM, Kim JM. Antioxidant and antimicrobial activities of propolis from several regions of Korea. LWT Food Sci Technol 2006;39:756-61.

Dharani MB, Sumathi S, Sivaprabha J, Padma PR. In vitro antioxidant potential of Prosopis cineraria. J Nat Prod Pant Resour 2011;1:26-32.

Lee JC, Kim Hr, Kim J, Jang ys. Antioxidant property of an ethanol extract of the stem of opuntia ficus-indica var. saboten. J Agric Food Chem 2002;50:6490-5496.

Hu C, Kitts DD. Studies on the antioxidant activity of Echinacea root extract. J Agric Food Chem 2000;48:1466-72.

Chirinos R, Betalleluz-Pallardel I, Huaman A, Arbizu C, Pedreschi R, Campos D. HPLC-DAD characterization of phenolic compounds from Andean oca (Oxalis tuberose Mol.) tubers and their contribution to the antioxidant capacity. Food Chem 2009;113:1243-51.

Shahidi F, Wanasundra PKJPD. Phenolics antioxidants critical reviews. Food Sci Nutr 1992;32:67-103.

Umamaheswari M, Chatterjee TK. In vitro antioxidant activities of the fractions of Coccinia grandis L. leaf extract. Afr J Tradit Complementary Altern Med 2008;5:61-73.

Sahoo AM, Chakraborti CK, Nayak S, Kayal S. Correlation between phytochemical screening and in vitro antibacterial activity study of Rosa indica leaves. Int J Res Ayurveda Pharm 2011;2:1595-7.

Valsaraj R, Pushpangathan P, Smitt UW. Antimicrobialscreening of selected medicinal plants from India. J Ethnopharmacol 1997;58:75-83.

Perumal Samy R, Ignachimuthu S, Sen A. Screening of 34 Indian medicinal plants for antibacterial properties. J Ethnol Pharmacol 1998;62:173-82.

Damle M. Glycyrrhiza glabra (Liquorice)-a potent medicinal herb. Int J Herb Med 2014;2:132-6.

Chopra PKPG, Saraf BD, Inam F, Deo SS. Antimicrobial and antioxidantactivities of methanol extract roots of glycyrrhiza glabra and HPLC analysis. Int J Pharm Pharm Sci 2013;5:157-60.

Sharma V, Agarwal RC, Pandey S. Phytochemical screening and determination of anti-bacterial and antioxidant potential of Glycyrrhiza glabra root extracts. J Environ Res Dev 2013;7:1552-8.

Dharmananda S. Gallnuts and the uses of tannins in Chinese medicine. In: Proceedings of Institute for Traditional Medicine, Portland, OR, USA; 2003.

Noboti T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994;368:753-6.

Ganguly T, Sainis KB. Inhibition of cellular immune responses by Tylophora indica in experimental models. Phytomedicine 2001;8:348-55.

Tamil SA, Dinesh MG, Satyan RS, Chandrasekaran B, Rose C. Leaf and seed extracts of Bixa orellana L. exerts anti-microbial activity against bacterial pathogens. J Appl Pharm Sci 2011;1:116-20.

Chakotiya AS, Chawla R, Tomar M, Thakur P, Goel R, Narula A, et al. In silico herbal bioprospection targeting multi-drug resistant Pseudomonas aeruginosa. Int J Interdiscip Multidiscip Stud 2014;2:163-76.

Published

21-09-2017

How to Cite

A., J., K. P. K., E. D., H. P., B. M., V. K., and S. Ravi. “PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF MILLINGTONIA HORTENSIS (L)”. International Journal of Current Pharmaceutical Research, vol. 9, no. 5, Sept. 2017, pp. 162-7, doi:10.22159/ijcpr.2017v9i5.2217.

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