• C. Nagaratnam Department of Pharmacology, Santhiram Medical College and General Hospital, Nandyal,
  • B. Deepika Department of Pharmacology, Prathima Medical College, Karimnagar,
  • C. Deepalatha Patient Safety Pharmaco Vigilance Technical Associate, Bhaskar General Hospital


Objective: To evaluate prevalence of cutaneous adverse reactions in young adult age group using ADR notification form. To create awareness in hospitals and health sectors, to establish drug safety monitoring units for mother and child care.

Methods: Individual case safety reports of 46 patients from various hospitals were analyzed using CDSCO forms. To tabulate data on drugs, doses, systems, ADRs and factors for causation of cutaneous ADRs.

Results: Females are more prone compared to males due to pregnancy at young age with increased use of Iron combinations, antibiotics and antiepileptic's in young adult age groups (20-30yrs) among cutaneous ADRs.

Conclusion: We conclude the need for establishment of drug safety units with generic units for maternity sections and use of drugs in pre and post natal period, as pregnancy and adult age are risk factors for cutaneous adverse drug reactions. Every hospital structure needs special caution on drug lots of iron preparations, antibiotics, analgesics, antiepileptic's to be used in Obstetrics and Gynecology departments.

Keywords: Cutaneous ADRs, Antibiotics, Iron preparations, Drug safety units


1. Chatterjee S, Ghosh AP, Barbhuiya J, Dey S. Adverse cutaneous drug reactions: A one year survey at a dermatology outpatient clinic of a tertiary care hospital. Indian J Pharmacol 2006;38:429-31.
2. Moore N, Lecointre D, Noblet C, Mabile M. Frequency and cost of serious adverse drug reactions in a department of general medicine. BR J Clin Pharmacol 1998;45:301-8.
3. Roujeau JC, Stern RS. Severe adverse cutaneous reactions to drugs. N Engl J Med 1994;331:1272-85.
4. Bilimoria FE, Shah BE. Drug reactions. In: Valia RG, Valia RR. IAVDL textbook of dermatology.3rd edition. India Blalani Publication; 2008. p. 1633-68.
5. World Health Organisation. Collaborating centre for International Drug Monitoring. Geneva: World Health Organization. WHO publication DEM/NC/8; 1984.
6. Pir Mohamed M, Breckenridge AM, Kitteringham NR, Park BK. Adverse drug reactions. Br Med J 1998;316:1295-8.
7. Deepa Latha Ciddhavaduta, Samee Knuta, Deepika Baloju. Analysis of cutaneous adverse drug reactions on using commonly prescribed drugs at a tertiary care hospital. J Evidence Based Med 2018;5:2349-2570.
8. Nayak S, Acharya B. Adverse cutaneous drug reaction. Indian J Dermatol 2008;53:2-8.
9. Breathnach SM, Hinter H. Adverse drug reactions and the skin. Oxford: Blackwell Scientific; 1992.
10. Sharma VK, Sethuraman G. Adverse cutaneous reactions to drugs: an overview. J Postgrad Med 1996;4:15-22.
235 Views | 257 Downloads
How to Cite
Nagaratnam, C., B. Deepika, and C. Deepalatha. “DRUG UTILIZATION PATTERN STUDY IN YOUNG ADULT PATIENTS OF CUTANEOUS ADVERSE DRUG REACTIONS”. International Journal of Current Pharmaceutical Research, Vol. 10, no. 6, Nov. 2018, pp. 13-15, doi:10.22159/ijcpr.2018v10i6.30965.
Original Article(s)