PHYTOCHEMICAL PROFILING OF MEDICALLY SIGNIFICANT CRUDE EXTRACT USING GC-MS ANALYSIS
Keywords:Kidney stone, Crude extract, GCMS analysis, Bioactive compounds
Objective: The objective of this research is to identify the phytochemical constitutions present in Natural crude extract which obtained from Thumlappati district.
Methods: Kidney stone is one of the most clinical disorder arising nowadays. They are existing due to the depletion of the urine and disproportionate execration of the components such as oxalate, phosphate, uric, cysteine, and struvite. Many alopathy medicine are not effectively curable in the case of kidney stone, consequently people are in need of traditional medicine system. Thus there is a great demand for research on potential inhibitor from natural products for dissolving kidney stone. In present work deals with an unknown crude extract collected from G. Thumlappati, Battalagundu Dindugal district Tamil Nadu. The crude extract of phytochemical are analyzed by using GCMS method.
Results: Thus the sample has some bioactive compound to discharge the stone particles. So we subjected the crude extract sample to GC-MS process which reveals 210 compounds in 21 different peaks.Conclusion: This studies forms a basis for the biological characterization and importance of bioactive compounds were identified.
Ayitey Smith E, Addae Mensah IW. Afr J Pharmacol Drug Res 1997;4:7-8.
Gill LS. Ethanobotanical uses of plants in Nigeria: university of Benin press: Benin city; 1992. p. 350.
Banso A, Adeyemo So. Evaluation of antibacterial properties of tannins isolated from dichrostachys cinerea. Afr J Biotechnol 2007;6:1785-7.
Pushpangadan P, Atal CK. Ethano-medico-botanical Investigations ir. Kerala I. Some primitive tribal of Western Ghats and their herbal medicine. J Ethanopharmacol 1984;11:59-77.
WHO, IUCN, WWF. Guidelines on the conservation of medicinal plants. Switzerland: IUCN Gland; 1993.
Home page on the Internet, World Health Organization. Available from: http://www.who.int/medicines/areas/traditional/definitions/en/. [Last accessed on 05 Jun 2018]
Jana S, shekhawat GS. Phytochemical analysis and antibacterial screening of in vivo and in vitro extracts of Indian medicinal herb: Anethum graveolens. Res J Med Plant 2010;4:206-12.
Levey AS, Atkins R, Coresh J. Chronic kidney disease as a global public health problem: approaches and initiatives-a position statement from kidney disease improving global outcomes. Kidney Int Aug 2007;72:247-59.