PHARMACEAUTICAL CARE IMPROVED THE QUALITY OF LIFE OF PATIENT WITH HEMODIALYSIS

  • ASYRUN ALKHAIRI LUBIS Departemen of Pharmacology, Faculty of Pharmacy, Sumatera Utara University Rasyida Kidney Hospital, Medan, Indonesia
  • AZIZAH NASUTION Departemen of Pharmacology, Faculty of Pharmacy, Sumatera Utara University Rasyida Kidney Hospital, Medan, Indonesia
  • ROSIDAH Departemen of Pharmacology, Faculty of Pharmacy, Sumatera Utara University Rasyida Kidney Hospital, Medan, Indonesia

Abstract

Objective: Patients undergoing hemodialysis in the long term often experience complications that affect the quality of life (QOL) of the patients. Comprehensive health services are very important for improving the QOL of the patients with chronic renal failure undergoing hemodialysis. The purpose of this study was to prove that the provision of therapy with pharmaceutical care can improve the QOL of hemodialysis patients.


Methods: This research was a quasi-experimental study pre and post test design. Samples were recruited applying the purposive sampling method. As many as 50 patients met the inclusion criteria and were asked to fill out the World Health Organization Quality Of Life (WHOQOL) questionnaire to measure their QOLs before and after the provisions of pharmaceutical care. Data obtained before and after pharmaceutical care were tested using paired t test, person correlation test, and Wilcoxon test in the program of SPSS 19.


Results: The results showed women more often experience complications when hemodialysis (62%), sex with quality of life (p = 0.907), education with quality of life (p = 0.277), work with quality of life (p = 0.582) length of undergoing hemodialysis with quality life (p = 0.733) no significant effect. Age (p = 0.044) significantly influences quality of life. And the average quality of life before administration of pharmacy and care was 48.12±5.98, while the quality of life after administration of therapy with pharmaceutical care was 50.16±6.22. Based on the Wilcoxon test, this value was significantly different (p = 0.009).


Conclusion: The conclusion of this study is the provision of therapy accompanied by pharmaceutical care significantly improves the quality of life of hemodialysis patients.

Keywords: Quality of life, Hemodialysis, Pharmaceutical care, Hemodialysis complications

References

1. Kaze FF, Ashuntantang G, Kengne AP. Acute hemodialysis complication in end-stage renal disease patients: the burden and implication for the under-resourced Sub-Saharan African Health system. Hemosial Int 2012;16:526-31.
2. Landry DW, Oliver JA. Blood pressure instability during hemodialysis. Kid Int 2006;69:1710–1.
3. Tatsuya S, Tsubakihara Y, Fujii M, Imai E. Hemodialysis-associated hypotension as an independent risk factor for two-year mortality in hemodialysis patients. Kidney Int 2004;66:1212–20.
4. Agustriadi O. Hubungan antara perubahan volume darah relatif dan episode hipotensi intradialitik selama hemodialisis pada gagal ginjal kronik (karya akhir). Denpasar: UniversitasUdayana; 2009.
5. Weisbord SD, Fried LF, Arnold RM, Fine MJ, Levenson DJ, Peterson RA, et al. Prevalence, severity, and importance of physical 91 and emotional symptoms in chronic hemodialysis patients. J Am Soc Nephrol 2005;16:2487-94.
6. Burton JO, Korsheed S, Grundy BJ, McIntyre CW. Hemodialysis-induced left ventricular dysfunction is associated with an increase in ventricular arrhythmias. Ren Fail 2008;7:701-9.
7. Herzog CA, Mangrum JM, Passman R. Sudden cardiac death and dialysis patients. Semin Dial 2008;21:300-7.
8. Kobrin SM, Berns JS. Quinine--a tonic too bitter for hemodialysis-associated muscle cramps? Semin Dial 2007:20:396-401.
9. Jesus AC, Oliveira HA, Paixao MO, Fraga TP, Barreto FJ, Valenca MM. Clinical description of hemodialysis headache in end-stage renal disease patients. Arq Neuropsiquiatr 2009;7:978-81.
10. Budiarto dan Anggraeni. Pengantar Epidemiologi, Edisi 2. Jakarta. EGC; 2002.
11. Rahman ARA, Rudiansyah M, Triawanti. Hubungan antara adekuasi hemodialisis dan kualitas hidup pasien di RSUD Ulin Banjarmasin; 2013. Available from: http://unnes.ac.id/. [Last accessed on 07 Nov 2013]
12. Lacson EJR, Xu J, Lin SF, Dean SG, Lazarus JM, Hakim RM. A comparasion of SF-36 and SF-12 composite score and subsequent hospitalization and mortality risks in long-term dialysis patient. Clin Sci USA; 2010.
13. World Health Organization. Management of substance abuse: WHO Quality of Life-BREF (WHOQOL-BREF); 2016. Available from: http://www/who.int. [Last accessed on 07 Nov 2013]
14. Suhud M. Cuci darah demi kualitas hidup, Kompas Syb; 2005.
15. Brunner and Suddarth. Buku Ajar Keperawatan Medikal Bedah, Ed 8. Jakarta: EGC; 2002.
16. Indonesian Renal Registry (IRR). Report of Indonesian Renal Registry 2011. PerhimpunanNefrologi Indonesia (PERNEFRI); 2013.
17. Weinstein JR, Anderson S. The aging kidney: physiological changes. Nih Public Access 2010;17:302-7.
18. Bakirci T, Sasak G, Ozturk S, Akcay S, Sezer S, Maberal M. Pleural effusion in long term hemodialysis patients. Transplantation Proceeding 2007;39:889-91.
19. Eva Sulistiowati, Sri Idaiani. Faktor risiko penyakit ginjal kronik berdasarkan analisis cross-sectional data awal studi kohort penyakit tidak menular penduduk usia 25-65 tahun di kelurahan kebon kalapa. Buletin Penelitian Kesehatan 2015;1:14-7.
20. Salawati L. Analisis lama hemodialisis dengan status gizi penderita penyakit ginjal kronik. Jurnal Kedokteran Syiah Kuala 2016;16:64-8.
21. Sutikno E. Hubungan fungsi keluarga dengan kualitas hidup lansia. Tesis, Surakarta: Universitas Sebelas Maret; 2011.
22. Wangsarahardja K. Kebutuhan pelayanan kesehatan gigi dan mulut pada masyarakat berpenghasilan rendah. Sci J Dentistry 2007;22:90-9.
23. Wig NL, Pal H, Ahuja V, Mittal C, Mohan, Agarwal S. The impact of HIV/AIDS on the quality of life: a cross sectional study in North India. Indian J Med Sci 2006;60:3-11.
24. Rahman, Moch TSA, Kaunang, Theresia MD, Elim C. Hubungan antara lama menjalani hemodialisa dengan kualitas hidup pasien yang menjalani hemodialisa di unit hemodialisa RSUP. Prof. Dr. R. D. Kandou Manado. J e-Clinic (eCl); 2016. p. 4.
25. Puspita DS. Hubungan lama hemodialisis dengan pasien gagal ginjal di RS PKU Muhammadiyah Yogyakarta (dissertation). Ilmu Keperawatan. [Yogyakarta]: Sekolah Tinggi Ilmu Kesehatan ’Aisyiyah; 2015.
26. Jesus AC, Oliveira HA, Paixao MO, Fraga TP, Barreto FJ, Valença MM. Clinical description of hemodialysis headache in end-stage renal disease patients. Arq Neuropsiquiatr 2009;7:978-81.
27. KDOQI Clinical Practice Guidelines for Cardiovascular Disease in Dialysis patients: NKF KDOQI Guidelines, National Kidney Foundation Inc; 2015.
28. Thomas D, Joseph J, Francis B, Mohanta GP. Effect of patient counseling on quality of life of hemodialysis patients in India. Pharm Pract (Granada) 2009;7:181-4.
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LUBIS, A. A., A. NASUTION, and ROSIDAH. “PHARMACEAUTICAL CARE IMPROVED THE QUALITY OF LIFE OF PATIENT WITH HEMODIALYSIS”. International Journal of Current Pharmaceutical Research, Vol. 11, no. 6, Nov. 2019, pp. 49-54, doi:10.22159/ijcpr.2019v11i6.36341.
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