ANALYSIS OF BIOACTIVE COMPOUNDS AND ANTIOXIDANT ACTIVITY OF PRUNUS CERASUS (SOUR CHERRY)

  • NAGENDAR SHETTY Renatus Wellness Pvt. Ltd. Bengaluru, India, 2Binod Bihari Mahto Koyalanchal University, Dhanbad, India
  • INDU Renatus Wellness Pvt. Ltd. Bengaluru, India, 2Binod Bihari Mahto Koyalanchal University, Dhanbad, India

Abstract

Objective: Prunus cerasus L. is consumed as a dietary supplement to promoting health benefits. The purpose of this study was to investigate the phenol and flavonoids content of sour cherry methanol extract in terms of antioxidant activity.


Methods: The content of polyphenols and flavonoids was quantified. DPPH and FRAP assay were used to evaluate the radical scavenging properties and reducing the antioxidant power of sour cherry fruit.


Results: DPPH scavenging activity was evaluated IC50 10.32±2.23 mg/ml and FRAP was estimated at 205±30 µmol/g.


Conclusion: Sour cherry methanol extract includes various bioactive compounds like polyphenols, flavonoids and anthocyanidins, which can be valuable beneficial effects to the prevention of various vascular diseases.

Keywords: Antioxidant, DPPH, FRAP, Prunus cerasus, Flavonoids

References

1. Ferretti G. Cherry antioxidants: from farm to table. Molecules 2010;15:6993-7005.
2. Mulabagal V, Lang GA, DeWitt DL, Dalavoy SS, Nair MG. Anthocyanin content, lipid peroxidation and cyclooxygenase enzyme inhibitory activities of sweet and sour cherries. J Agric Food Chem 2009;57:1239-46.
3. Wang H, NairMG, Strasburg GM. Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod 1999;62:294–6.
4. Wojdy?o A, Figiel A, Lech K, Nowicka P, Oszmian?ski J. Effect of convective and vacuum-microwave drying on the bioactive compounds, colour and antioxidant activity of sour cherries. Food Bioprocess Technol 2014;7:829?41.
5. Khoo GM, Clausen MR, Pedersen H, Larsen E. Bioactivity and total phenolic content of 34 sour cherry cultivars. J Food Comp Anal 2001;24:772?6.
6. Rice Evans C. Screening of phenolics and flavonoids for antioxidant activity. In: Packer L, Hiramatsu M, Yoshikawa T. eds. Antioxidant Food Supplements in Human Health. SanDiego, Calif: Academic Press; 1999. p. 239–53.
7. Kamei H, Kojima S, Hasegawa M, Umeda T, Terabe K, Yukawa T. Suppressive effect of flavonoid extracts from flower petals on cultured human malignant cells. J Clin Exp Med 1993;164:829–30.
8. Bomser J, Madhavi DL, Singletary K, Smith MA. In vitro anticancer activity of fruit extracts from Vaccinium species. Planta Med 1996;62:212–6.
9. Wang H, Nair MG, Iezzoni A, Strasburg GM, Booren AM, Gray JI. Quantification and characterization of anthocyanins in balaton tart cherries. J Agric Food Chem 1997;45:2556–60.
10. Wang H, Nair MG, Strasburg GM. Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod 1999;62:294–6.
11. Kang SY, Seeram NP, Nair MG, Bourquin LD. Tart cherry anthocyanins inhibit tumor development in ApcMin mice and reduce proliferation of human colon cancer cells. Cancer Lett 2003;194:13–9.
12. Zhishen J, Mengcheng T, Jianming W. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem 1999;64:555–9.
13. V Lopez, S Akerreta, E Casanova, JM Garcia Mina, RY Cavero, MI Calvo. In vitro antioxidant and antirhizopus activities of Lamiaceae herbal extracts. Plant Foods Hum Nutr 2007;62:151–5.
14. Oyaizu M. Studies on products of the browning reaction. Antioxidative activities of browning reaction products prepared from glucosamine. Japan J Nutr 1986;44:307–14.
15. Bomser J, Madhavi DL, Singletary K, Smith MA. In vitro anticancer activity of fruit extracts from Vaccinium species. Planta Med 1996;62:212–6.
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SHETTY, N., and INDU. “ANALYSIS OF BIOACTIVE COMPOUNDS AND ANTIOXIDANT ACTIVITY OF PRUNUS CERASUS (SOUR CHERRY)”. International Journal of Current Pharmaceutical Research, Vol. 12, no. 2, Mar. 2020, pp. 4-5, doi:10.22159/ijcpr.2020v12i2.37476.
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