SENSITIVITY AND SPESIFICITY VALUE OF PLATELETS, MALIGNANCY RATIO INDEX AND BOTH COMBINED IN DIAGNOSING OVARIAN CANCER AT GENERAL HOSPITAL HAJI ADAM MALIK MEDAN FROM 2016-2018

  • YOVITA V. Department of Obstetric and Gynaecology, Medical Faculty, Universitas Sumatera Utara, General Hospital of H. Adam Malik
  • TALA MRZ Urogynecology Division, Department of Obstetric and Gynaecology, Medical Faculty, Universitas Sumatera Utara, General Hospital of H. Adam Malik
  • DINA S. Oncology Gynecology Division, Department of Obstetric and Gynaecology, Medical Faculty, Universitas Sumatera Utara, General Hospital of H. Adam Malik
  • LUMBANRAJA S. N. Feto Maternal Division, Department of Obstetrics and Gynaecology, Medical Faculty, Universitas Sumatera Utara, General Hospital of H. Adam Malik
  • LUBIS D. L. Urogynecology Division, Department of Obstetric and Gynaecology, Medical Faculty, Universitas Sumatera Utara, General Hospital of H. Adam Malik
  • ADELLA C. A. Oncology Gynecology Division, Department of Obstetric and Gynaecology, Medical Faculty, Universitas Sumatera Utara, General Hospital of H. Adam Malik

Abstract

Objective: This research aimed to analyze sensitivity and specificity values of platelets, RMI and both combined as ovarian cancer diagnostic modality in Haji Adam Malik Hospital in 2016-2018.


Methods: This is analytic research with a diagnostic test design on 204 patients who had been diagnosed with ovarian cancer and patients with ovary benign tumors which have been examined the value of full blood and the malignancy ratio index and ovarian mass that has been proven by the results of anatomic pathology at General Hospital Haji Adam Malik Medan in 2016-2018. The data is tabulated into 2x2 table and then calculated for each sensitivity, specificity, positive predictive value and negative predictive value.


Result: By using platelet cut-off value>450000 per mm3 in diagnosing ovarian cancer with sensitivity 55.44% and specificity 83.65% were obtained. IRK has a sensitivity 83.16% and specificity 76.92%. Platelet and IRK values ​​provided the highest diagnostic value (specificity) compared to when they were each single which was 97.11% while the combination of platelet and IRK values ​​had a sensitivity of 49.50%.


Conclusion: Platelet and IRK values ​​gives the highest diagnostic value (specificity) compared to when both are used, namely 97.11%.

Keywords: Sensitivity, Specificity, Platelets, Malignancy Ratio Index

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V., Y., T. MRZ, D. S., L. S. N., L. D. L., and A. C. A. “SENSITIVITY AND SPESIFICITY VALUE OF PLATELETS, MALIGNANCY RATIO INDEX AND BOTH COMBINED IN DIAGNOSING OVARIAN CANCER AT GENERAL HOSPITAL HAJI ADAM MALIK MEDAN FROM 2016-2018”. International Journal of Current Pharmaceutical Research, Vol. 12, no. 3, May 2020, pp. 121-5, doi:10.22159/ijcpr.2020v12i3.38320.
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