• SWARNALI ROY Department of Bioscience and Engineering, Jadavpur University, 188, Raja S. C. Mallick Road, Kolkata 700032, India
  • SANKHADIP BOSE Department of Pharmacognosy, Bengal School of Technology, Sugandha, Delhi Road, Chuchura, Hooghly, West Bengal 712102, India
  • DHRUBAJYOTI SARKAR Department of Pharmaceutical Technology, NSHM Knowledge Campus, Kolkata–Group of Institutions, 124, B. L Saha Road, Kolkata 700053, India
  • SANJIT MANDAL Department of Pharmaceutical Chemistry, Bengal College of Pharmaceutical Science and Research, Durgapur, West Bengal 713212, India,
  • SIPRA SARKAR Department of Pharmaceutical Technology, Brainware University, 398-Ramkrishnapur, Road, Barasat, Kolkata-700125, West Bengal, India
  • SUDIP KUMAR MANDAL Department of Pharmaceutical Chemistry, Dr. B. C. Roy College of Pharmacy and Allied Health Sciences, Durgapur 713206, West Bengal, India



Acne vulgaris, Murraya koeinigii, Propionibacterium acne


Objective: Acne, one among the very fashionable socially distressing skin conditions created by Propionibacterium acne have generally been treated by antibiotics. Within the light of the growing threat of antibiotic resistance, natural plant products are applied as a safer alternative. Keeping the very fact in the background, during this research work, the formulation of gel from the extracts of Murraya koeinigii leaves are prepared and evaluated as an anti-acne drug.

Methods: The fresh leaf extracts were subjected to phytochemical and antimicrobial screening. Minimum Inhibitory Concentration (MIC) decided. Gel formulation of the extracts was developed and evaluated. The manufactured formulations were subjected to In vitro antibacterial activity against P. acnes, S. epidermidis and S. aureus. The marker compound, clindamycin, in herbal anti-acne preparation, was kept for the comparison with the zones of inhibition for antibacterial activity.

Results: Anti-acne property was explored with the help of a standard curve and by comparing diffusion profiles by taking clindamycin as a reference.

Conclusion: From the present study it can be concluded that addition of permeation enhancer in the test formulation will improve the diffusion profile and thus it was designed to add permeation enhancer.


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How to Cite

ROY, S., S. BOSE, D. SARKAR, S. MANDAL, S. SARKAR, and S. K. MANDAL. “FORMULATION AND EVALUATION OF ANTI-ACNE GEL CONTAINING MURRAYA KOEINIGII EXTRACT”. International Journal of Current Pharmaceutical Research, vol. 12, no. 4, July 2020, pp. 108-13, doi:10.22159/ijcpr.2020v12i4.39095.



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