EFFECT OF PSQI SCORE ON ADMINISTRATION MELATONIN IN PERIMENOPAUSE WOMEN

  • HANDRI R. VEBRIAN Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sumatera Utara
  • MUHAMMAD FIDEL GANISSIREGAR Reproductive Endocrinology and Fertility Division, Departmen od Obstetrics and Gynecology Faculty of Medicine, Universitas Sumatera Utara
  • ICHWANUL ADENIN Reproductive Endocrinology and Fertility Division, Departmen od Obstetrics and Gynecology Faculty of Medicine, Universitas Sumatera Utara
  • HERBERT SIHITE Fetomaternal Division, Departmen od Obstetrics and Gynecology Faculty of Medicine, Universitas Sumatera Utara
  • EDY ARDIANSYAH Urigynecology Division, Departmen od Obstetrics and Gynecology Faculty of Medicine, Universitas Sumatera Utara
  • SARAH DINA Oncology Gynecology Division, Departmen od Obstetrics and Gynecology Faculty of Medicine, Universitas Sumatera Utara
  • PUTRI C. EYANOER Department of Community and Preventive Medicine, Faculty of Medicine, Universitas Sumatera Utara

Abstract

Objective: Determine the effect of melatonin administration on sleep quality perimenopausal women based on PSQI and compare the results of PSQI before and after treatment.


Methods: This study uses an experimental analytic study with Case Control design to determine the effect of melatonin administration on sleep quality perimenopausal women based on PSQI and compare the results of PSQI before and after treatment. This research was conducted at the Department of Obstetrics and Gynecology, H. Adam Malik General Hospital, Medan. The study population was all perimenopausal women who met the inclusion and exclusion criteria. This research was conducted from February to March 2020 with a sample of 25 people.


Results: PSQI scores in the control group by age were 4.0±1.0 in the age group>50 y from 8.0±1.0; 2.17±1.62 in the group with tertiary education from 5.83±1.69; 2.56±1.67 in the non-working group of 6.44±1.51 and 2.31±1.6 in the multipara group of 6.0±1.58. From the analysis results obtained a value of P<0.001. This also showed a significant difference in the PSQI score in the control group. significant differences in PSQI values ​​in the control group and melatonin group in the case group before getting melatonin (p<0.001), whereas after administering melatonin, no difference in PSQI score was found in the groups that received melatonin and the control group (p = 0.657)


Conclusion: There are differences in PSQI scores in the case group before and after the administration of melatonin, in the control group who did not get melatonin and the difference in PSQI scores in the case group and the control group before treatment, but there were no differences in PSQI score in the case and control groups after treatment.

Keywords: Perimenopause, Melatonin, PSQI

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VEBRIAN, H. R., M. F. GANISSIREGAR, I. ADENIN, H. SIHITE, E. ARDIANSYAH, S. DINA, and P. C. EYANOER. “EFFECT OF PSQI SCORE ON ADMINISTRATION MELATONIN IN PERIMENOPAUSE WOMEN”. International Journal of Current Pharmaceutical Research, Vol. 12, no. 4, July 2020, pp. 118-21, doi:10.22159/ijcpr.2020v12i4.39097.
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