ANTIMICROBIAL EVALUATION OF ETHANOLIC EXTRACT OF SELECTED SEED SHELLS

  • MOUSHUMI BAIDYA Department of Pharmaceutical Technology, JIS University, Agarpara, Kolkata 700109, West Bengal, India, Department of Pharmaceutical Technology, Brainware University, Barasat 700125, West Bengal, India
  • ANBU J. Department of Pharmacology, Faculty of Pharmacy, M. S. Ramaiah University of Applied Sciences, MSR Nagar, Bangalore 560054, Karnataka, India
  • SEMIMUL AKHTAR Shri Ram Murti Smarak College of Engineering and Technology (Pharmacy), Bareilly, Uttar Pradesh, India
  • SIPRA SARKAR Department of Pharmaceutical Technology, Brainware University, Barasat 700125, West Bengal, India
  • SUDIP KUMAR MANDAL Department of Pharmaceutical Chemistry, Dr. B. C. Roy College of Pharmacy and Allied Health Sciences, Durgapur 713206, West Bengal, India

Abstract

Objective: The study was undertaken to evaluate the antimicrobial activity of ethanolic extract of polyherbal seed shells.


Methods: The seed of Momordica charantia, Manikara zapota, Emblica officinalis, Syzygium cumini, collected from the local market, Mathikere, Bangalore, India. Ethanolic extract was prepared from the dried seed powders using solvent 80% ethanol. Initially, antimicrobial activity of the extract was performed by agar well diffusion method against two bacterial strains (Escherichia coli, and Staphylococcus aureus) and two fungal pathogens (Aspergillus niger and Candida albicans).


Results: The antimicrobial study results revealed that the test extract was strongly inhibited the growth of bacteria, whereas it was not inhibited the growth of fungal organisms used in this study.


Conclusion: The results suggest that ethanolic extract of seeds possess antimicrobial properties which can be used for the treatment of infectious diseases.

Keywords: Antibacterial, Antifungal, Polyherbal seeds extract

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BAIDYA, M., A. J., S. AKHTAR, S. SARKAR, and S. K. MANDAL. “ANTIMICROBIAL EVALUATION OF ETHANOLIC EXTRACT OF SELECTED SEED SHELLS”. International Journal of Current Pharmaceutical Research, Vol. 12, no. 6, Nov. 2020, pp. 74-76, doi:10.22159/ijcpr.2020v12i6.40286.
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