ANTIMICROBIAL EVALUATION OF ETHANOLIC EXTRACT OF SELECTED SEED SHELLS
Keywords:Antibacterial, Antifungal, Polyherbal seeds extract
Objective: The study was undertaken to evaluate the antimicrobial activity of ethanolic extract of polyherbal seed shells.
Methods: The seed of Momordica charantia, Manikara zapota, Emblica officinalis, Syzygium cumini, collected from the local market, Mathikere, Bangalore, India. Ethanolic extract was prepared from the dried seed powders using solvent 80% ethanol. Initially, antimicrobial activity of the extract was performed by agar well diffusion method against two bacterial strains (Escherichia coli, and Staphylococcus aureus) and two fungal pathogens (Aspergillus niger and Candida albicans).
Results: The antimicrobial study results revealed that the test extract was strongly inhibited the growth of bacteria, whereas it was not inhibited the growth of fungal organisms used in this study.
Conclusion: The results suggest that ethanolic extract of seeds possess antimicrobial properties which can be used for the treatment of infectious diseases.
2. Stephenson LS, Latham MC, Ottesen EA. Malnutrition and parasitic helminth Infections. Parasitology 2000;121:23-38.
3. Brooker S. Estimating the global distribution and disease burden of intestinal nematode infections: adding up the Numbers-a review. Int J Parasitol 2010;40:1137-44.
4. Strunz EC, Addiss DG, Stocks ME, Ogden S, Utzinger J, Freeman MC. Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis. PLoS Med 2014;11:1001620.
5. Utzinger J, Raso G, Brooker S, De Savigny D, Tanner M, Ornbjerg N, et al. Schistosomiasis and neglected tropical diseases: towards integrated and sustainable control and a word of caution. Parasitology 2009;136:1859.
6. Jia TW, Melville S, Utzinger J, King CH, Zhou XN. Soil-transmitted helminth reinfection after drug treatment: a systematic review and meta-analysis. PLoS Negl Trop Dis 2012;6:1621.
7. Sandhu DS, Heinrich M. The use of health foods, spices and other botanicals in the Sikh community in London. Phytother Res 2005;19:633-42.
8. Gupta MP, Solis PN, Calderon AI, Guionneau Sinclair F, Correa M, Galdames C, et al. Medical ethnobotany of the teribes of bocas del toro, panama. J Ethnopharmacol 2005;96:389-401.
9. Mandal SK. Indanyl analogs as potential antimicrobial agents. Asian J Pharm Clin Res 2018;11:278-80.
10. Roy S, Bose S, Sarkar D, Mandal S, Sarkar S, Mandal SK. Formulation and evaluation of anti-acne gel containing Murraya koeinigii extract. Int J Curr Pharma Res 2020;12:108-13.
11. Mandal SK, Pal H, Pal I, Bose S. Biological potential of Elephantopus scaber linn. Int J Pharm Sci Rev Res 2018;50:130-4.
12. Bose S, Mandal SK, Hossain P, Das A, Das P, Nandy S, et al. Phytochemical and pharmacological potentials of Agaricus bisporus. Res J Pharm Tech 2019;12:3811-7.
13. Mondal A, Bose S, Banerjee S, Patra J, Malik J, Mandal SK, et al. Marine cyanobacteria and microalgae metabolites-a rich source of potential anticancer drugs. Mar Drugs 2020;18:476.
14. Chakraborty GS. Antimicrobial activity of Chlorophytum borivilianum leaves. Indian Drugs 2009;46:579.
15. Rastogi T, Ghorpade DS, Deokate UA, Khadabadi SS. Studies on antimicrobial activity of Boswellia serrata, Moringa oleifera and Vitex negundo: a comparison. Res J Pharmacog Phytochem 2009;1:75-7.
16. Nithya M, Ragavendran C, Natarajan D. Antibacterial and free radical scavenging activity of a medicinal plant Solanum xanthocarpum. Int J Food Prop 2018;21:313-27.
17. Prakash SB, Sharmistha P, Kumar AR. Antibacterial activity of methanolic extract of roots of Caesalpinia pulcherrima. Int J Chem Sci 2009;7:16-8.