A RETROSPECTIVE STUDY OF THE PREVALENCE OF DEPRESSION DUE TO LOW HAEMOGLOBIN COUNT
Keywords:Depression, Anaemia, Haemoglobin count, Low haemoglobin, Ham D score, Anaemia effects, Anti-depressants
Objective: It has been shown that low haemoglobin count is associated with psychological consequences and psychiatric morbidity. The association between low haemoglobin count and psychological depression has not been properly interpreted with standard values. Hence the purpose of this pilot study is to know whether there is a relation between the haemoglobin levels and the risk of developing psychiatric disorders and morbidities.
To find out if there is any relationship between low haemoglobin count and depression in a rural healthcare setup.
Methods: Patients from the Psychiatry Department in Saveetha Medical College and Hospital were taken. Adults over the age of 18 were included. The period between the months September 2020 and July 2021. The primary outcome was the diagnosis of psychiatric depression and their associated blood haemoglobin values.
Results: Among the other types of psychiatric disorders, the female patients with low haemoglobin count were associated with a significantly higher incidence of anxiety disorders, depression and adjustment disorders. Furthermore, patients with normal haemoglobin levels were associated with a significantly lower risk of psychiatric morbidities.
Conclusion: The undergone study indicates that patients with psychiatric disorders such as depression, adjustment disorders and anxiety are related with significantly low haemoglobin counts in women and not in men.
Hamer M, Molloy GJ. Cross-sectional and longitudinal associations between anemia and depressive symptoms in the English Longitudinal Study of Ageing. J Am Geriatr Soc. 2009 May;57(5):948-9. doi: 10.1111/j.1532-5415.2009.02250.x, PMID 19470033.
Hidese S, Saito K, Asano S, Kunugi H. Association between iron‐deficiency anemia and depression: A web‐based Japanese investigation. Psychiatry Clin Neurosci. 2018 Jul;72(7):513-21. doi: 10.1111/pcn.12656, PMID 29603506.
Pereira B, Andrew G, Pednekar S, Pai R, Pelto P, Patel V. The explanatory models of depression in low-income countries: listening to women in India. J Affect Disord. 2007 Sep 1;102(1-3):209-18. doi: 10.1016/j.jad.2006.09.025, PMID 17074394.
Thein M, Ershler WB, Artz AS, Tecson J, Robinson BE, Rothstein G, Liede A, Gylys-Colwell I, Lu ZJ, Robbins S. Diminished quality of life and physical function in community-dwelling elderly with anemia. Medicine. 2009 Mar;88(2):107-14. doi: 10.1097/MD.0b013e31819d89d5, PMID 19282701.
Silverman J, Krieger J, Kiefer M, Hebert P, Robinson J, Nelson K. The relationship between food insecurity and depression, diabetes distress and medication adherence among low-income patients with poorly controlled diabetes. J Gen Intern Med. 2015 Oct;30(10):1476-80. doi: 10.1007/s11606-015-3351-1, PMID 25917659.
Gholamreza Noorazar S, Ranjbar F, Nemati N, Yasamineh N, Kalejahi P. Relationship between severity of depression symptoms and iron deficiency anemia in women with major depressive disorder. Res Clin Med. 2015 Nov 30;3(4):219-24.
Trevisan C, Veronese N, Bolzetta F, De Rui M, Correll CU, Zambon S, Musacchio E, Sartori L, Perissinotto E, Crepaldi G, Solmi M, Manzato E, Sergi G. Low hemoglobin levels and risk of developing depression in the elderly: results from the prospective PRO. VA study. J Clin Psychiatry. 2016 Dec 28;77(12):e1549-56. doi: 10.4088/JCP.15m10270.
Vahdat Shariatpanaahi M, Vahdat Shariatpanaahi Z, Moshtaaghi M, Shahbaazi SH, Abadi A. The relationship between depression and serum ferritin level. Eur J Clin Nutr. 2007 Apr;61(4):532-5. doi: 10.1038/sj.ejcn.1602542, PMID 17063146.
Bodnar LM, Wisner KL. Nutrition and depression: implications for improving mental health among childbearing-aged women. Biol Psychiatry. 2005 Nov 1;58(9):679-85. doi: 10.1016/j.biopsych.2005.05.009, PMID 16040007.
Dogan E, Erkoc R, Eryonucu B, Sayarlioglu H, Agargun MY. Relation between depression, some laboratory parameters, and quality of life in hemodialysis patients. Ren Fail. 2005 Jan 1;27(6):695-9. doi: 10.1080/08860220500242728, PMID 16350820.
Ahmed T, Vasiliadis HM. Global cognition modifies the relationship between anemia and depression in old age: A longitudinal analysis of the IMIAS Study. Arch Gerontol Geriatr. 2021 May 1;94:104342. doi: 10.1016/j.archger.2021.104342.
Vulser H, Lemogne C, Boutouyrie P, Cote F, Perier MC, Van Sloten T, Hoertel N, Danchin N, Limosin F, Jouven X, Empana JP. Depression, antidepressants and low hemoglobin level in the paris prospective study III: A cross-sectional analysis. Prev Med. 2020 Jun 1;135:106050. doi: 10.1016/j.ypmed.2020.106050.
Eizadi Mood N, Ahmadi R, Babazadeh S, Yaraghi A, Sadeghi M, Peymani P, Sabzghabaee AM. Anemia, depression, and suicidal attempts in women: is there a relationship? J Res Pharm Pract. 2018 Jul;7(3):136-40. doi: 10.4103/jrpp.JRPP_18_25, PMID 30211238.
Leone T, Coast E, Narayanan S, de Graft Aikins A. Diabetes and depression comorbidity and socioeconomic status in low and middle-income countries (LMICs): a mapping of the evidence. Global Health. 2012 Oct;8(1):39. doi: 10.1186/1744-8603-8-39, PMID 23181626.
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