EVALUATION OFANTI-OXIDANT AND ANTI-ACNE ACTIVITIES (IN-VITRO) OF THE FORMULATED HERBAL GELS


Khushbu Pravin Shah, Rashmi Shukla Srivastava

Abstract


Objective: The objective of the present study was to evaluate the anti-oxidant and anti-acne activities (in-vitro) of the formulated herbal gels.

Methods: Herbal extracts and volatile oils were prepared and procured. Preliminary screenings for the anti-oxidant and anti-acne activities (in-vitro) were carried out to select the suitable candidates for the preparation of anti-acne herbal gels. Gels were further evaluated for the activities.

Results: The herbal gel (F2) containing the herbal extracts (Azadirachtaindica, Ocmium sanctum, Curcuma longa) each (1%) and volatile oils (Melaleucaalternifoliae, Salviaesclareae and Citrus sinensis) each (0.05%) showed maximum anti-oxidant activity (IC50 value 0.407 mg) amongst all four gels. Significant anti-acne activity against P. acne and S. epidermidis was showed by F2 when compared with the marketed synthetic gel (Clindac gel).

Conclusion: The study proves that the herbal actives used in the formulation have promising anti-oxidant and anti-acne activity.

Keywords: Herbal extracts, Volatile oils, Gelling agents, Anti-oxidant activity and anti-acne activity.

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References


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About this article

Title

EVALUATION OFANTI-OXIDANT AND ANTI-ACNE ACTIVITIES (IN-VITRO) OF THE FORMULATED HERBAL GELS
Date

15-07-2015

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 7, Issue 3, 2015 Page: 47-50
Online ISSN

0975-7066
Authors & Affiliations

Khushbu Pravin Shah
Mumbai Education Trust’s Institute of Pharmacy, MET Complex, Bandra Reclamation, Bandra (W), Mumbai 400050, India

Rashmi Shukla Srivastava
Mumbai Education Trust’s Institute of Pharmacy, MET Complex, Bandra Reclamation, Bandra (W), Mumbai 400050, India


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