@article{Narule_Gaidhane_Gaidhane_2015, title={ANTIOXIDANT AND PHARMACOLOGICAL ACTIVE MICROWAVE MEDIATED SYNTHESIS OF 2-(4/-PHENOTHIAZINYL PYRAZOLYL) PYRROLES}, volume={7}, url={https://journals.innovareacademics.in/index.php/ijcpr/article/view/4725}, abstractNote={<p>Phenothiazine derivatives substituted in the 2 and 10 positions belong to a big group of tricyclic aromatic compounds. They are in extensive use in psychiatry as tranquilizers and neuroleptics. Phenothiazines belong to an important class of heterocyclic compounds known for their pharmaceutical properties. Phenothiazine core is the active component in sedatives, tranquilizers, antituberculotics or bactericides. Phenothiazines are electron donor compounds with a low oxidation potential and they can form easily radical-cations. Lately phenothiazine has become very popular in material science or in biochemistry as marker for proteins and DNA.</p> <p>2-[4<sup>/</sup>-hydroxyl benz-1<sup>/</sup>-(propene-1<sup>//</sup>-one)] Pyrrole <strong>(2)</strong> on treatment with primary amine gives 2-[biphenyl amine-1<sup>/</sup>-(propane-1<sup>//</sup>-one)] pyrrole <strong>(3)</strong> which react with sulphur and iodine affording substituted 2-[phenothiazinyl-8<sup>/</sup>-(propane-1<sup>//</sup>-one)] pyrrole <strong>(4a-j)</strong> which undergoes cyclization with NH<sub>2</sub>. NH<sub>2</sub>H<sub>2</sub>O and Substituted 2-(4<sup>/</sup>-phenothiazinyl pyrazolyl) pyrrole <strong>(5a-j)</strong> is obtained. The structure products were characterized by elemental analysis and spectral data.</p>}, number={1}, journal={International Journal of Current Pharmaceutical Research}, author={Narule, Meghasham N. and Gaidhane, Mahesh K. and Gaidhane, Pravin K.}, year={2015}, month={Jan.}, pages={66–70} }