TY - JOUR AU - T. S., VISHWAS AU - B. M., GURUPADAYYA PY - 2019/09/15 Y2 - 2024/03/29 TI - NOVEL UV SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF TERIFLUNOMIDE IN TABLET DOSAGE FORM JF - International Journal of Current Pharmaceutical Research JA - Int J Curr Pharm Sci VL - 11 IS - 5 SE - Original Article(s) DO - 10.22159/ijcpr.2019v11i5.35711 UR - https://journals.innovareacademics.in/index.php/ijcpr/article/view/35711 SP - 81-84 AB - <p><strong>Objective</strong>: The current work is intended towards the development of a novel, simple, and precise UV spectrophotometric method for the estimation of teriflunomide (TEF) present in the marketed formulation.</p><p><strong>Methods</strong>: Acetonitrile was used as asolvent and the absorbance of the drug was measured at the absorbance maxima of TEF, UV 284 nm.</p><p><strong>Results</strong>: Calibration curve plotted in concentration range 5-10 µg /ml exhibited excellent linear relationship with line equation y = 0.0858x-0.0223 and r<sup>2</sup> value of 0.9996. The method was found to comply all the validation parameters as per the ICH guideline indicating the sensitivity of the method towards analyte.</p><p><strong>Conclusion: </strong>The method can be used satisfactorily for the routine analysis of TEF present in marketed formulation.</p> ER -