TY - JOUR AU - BAYAS-MOREJON, FAVIAN AU - TIGRE, ANGELICA AU - RAMON, RIVELINO AU - YANEZ, DANILO PY - 2020/03/15 Y2 - 2024/03/29 TI - ANTIMICROBIAL AND ANTIOXIDANT EFFECT OF NATURAL EXTRACTS FROM LEAVES, ROOT, STEM AND FLOWERS OF BACCHARIS LATIFOLIA FROM ECUADOR JF - International Journal of Current Pharmaceutical Research JA - Int J Curr Pharm Sci VL - 12 IS - 2 SE - Original Article(s) DO - 10.22159/ijcpr.2020v12i2.37495 UR - https://journals.innovareacademics.in/index.php/ijcpr/article/view/37495 SP - 78-84 AB - <p><strong>Objective: </strong>The increase in chronic and degenerative diseases and the use of synthetic antioxidants such as (butylated hydroxyanisole (BHA) or butylated hydroxytoluene (BHT)) are being restricted because they can be considered carcinogenic. Therefore, there is a growing interest in the search for natural antioxidants, especially from plants, due to their content in different bioactive compounds, such as antioxidants and antimicrobials. To evaluate the antibacterial and antioxidant activity of <em>Baccharislatifolia</em> extracts.</p><p><strong>Methods: </strong>For the determination of the antimicrobial activity of extracts of leaves, root, stem and flowers of <em>Baccharislatifolia</em> (<em>Bl</em>), the disk plate diffusion method was used, the strains of <em>Listeria</em>, <em>Salmonella</em> and <em>E. coli</em> were studied; antibiotics Penicillin G and Ciprofloxacin were the controls. For the antioxidant activity, a solution of H<sub>2</sub>O<sub>2</sub> (Abs at 230 nm) was prepared in Potassium Phosphate Monobasic-Sodium Hydroxide buffer.</p><p><strong>Results: </strong>The antimicrobial activity against <em>Listeria</em> and <em>Salmonella</em>, showed that the extracts of leaves and flowers were more effective with inhibition zones&gt;15 mm and&gt;20 mm respectively. In front of E. coli, the extracts of flowers and stem were the best with zones&gt;7.0 mm. Antibiotics studied inhibited the development of <em>Listeria</em> and <em>Salmonella</em>. However, <em>E. coli</em> isolates were resistant. In the antioxidant activity, the flower extract of Bl in 60 mg/ml presents a higher effect with 47.25%.</p><p><strong>Conclusion: </strong>Bl extracts from leaves and flowers were more efficient both in their antimicrobial and antioxidant capacity.</p> ER -