TY - JOUR AU - RUSLIN, AU - ASPADIAH, VICA AU - DHIANAWATY, DIAH PY - 2020/05/15 Y2 - 2024/03/29 TI - ANTIHYPERGLYCEMIC ACTIVITY OF IMPERATA CYLINDRICA ROOT METHANOL EXTRACT IN RATS JF - International Journal of Current Pharmaceutical Research JA - Int J Curr Pharm Sci VL - 12 IS - 3 SE - Original Article(s) DO - 10.22159/ijcpr.2020v12i3.38324 UR - https://journals.innovareacademics.in/index.php/ijcpr/article/view/38324 SP - 140-143 AB - <p><strong>Objective: </strong>This study aims to evaluate the inhibitory activity of <em>Imperatacylindrica</em> root methanol extract on glucose absorption level in intestine of male Wistar strain rats at a dose of 90 mg/kg-bw, which is a dose having antihypertensive activity.</p><p><strong>Methods: </strong>Extract inhibitory activity on the glucose absorption level in the intestine of the rats followed Soedigdo-Marsongkohadi method. Glucose absorption level was measured from a mixture of 30 mmol glucose in 0.9 % sodium chloride solution as the control solution and a mixture of the extract at the dose of 90 mg/kg-bw in another control solution as the tested solution</p><p><strong>Results: </strong>The result showed that the extract at the dose of 90 mg/kg-bw had significant activity (p&lt;0.05) to decrease the glucose absorption level in the intestine of the rats.</p><p><strong>Conclusion: </strong><em>I. cylindrica</em> root methanol extract at the dose of 90 mg/kg-bw had a significant activity to inhibit the glucose absorption level in the intestine of the rats. Thereby, the extract at the dose of 90 mg/kg-bw had antihyperglycemic activity.</p> ER -