CATHETER ASSOCIATED LEIFSONIA AQUATICA INFECTION
Objective: This is a case report of catheter-related infection caused by Leifsonia aquatica in a hemodialysis patient. Leifsonia aquatica is not a commonly isolated bacterium and not much is known about the virulence, pathogenesis of infection or choice of treatment.
Methods: A case report of a 65 years old man who presented with chills and rigors during hemodialysis via an internal jugular catheter.
Results: Leifsonia aquatica was isolated from the patient’s blood culture. The organism grew on conventional media and was identified using analytical profile index (API) Coryne. The patient was successfully treated with two weeks of ceftriaxone and the catheter was removed.
Conclusion: Leifsonia aquatica is an aquatic bacterium capable of causing infection in the immunocompromised host and its pathogenicity is related to its ability to form biofilms. Treatment based on antimicrobial susceptibility results and removal of the catheter is necessary for a patient’s recovery.
2. Evtushenko LI, Dorofeeva LV, Subbotin SA, Cole JR, Tiedje JM. Leifsonia poae gen. nov., sp. nov., isolated from nematode galls on Poa annua, and reclassification of ‘Corynebacterium aquaticum’ Leifson 1962 as Leifsonia aquatica (ex Leifson 1962) gen. nov., nom. rev., comb. nov. and Clavibacter xyli Davis et al. 1984 with two subspecies as Leifsonia xyli (Davis et al. 1984) gen. nov., comb. nov. Int J Syst Evol Microbiol 2000;50:371-80.
3. Weiner M, Werthamer S. Corynebacterium aquaticum septicemia. Characterization of the microorganisms. Am J Clin Pathol 1975;64:378 81.
4. Casella P, Bosoni MA, Tommasi A. Recurrent Corynebacterium aquaticum peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis. Clin Microbiol Newsl 1988;10:62-3.
5. Fujinaga S, Ohtomo Y, Hirano D, Nishizaki N, Someya T, Ohtsuka Y, et al. Relapsing peritonitis with Corynebacterium aquaticum in a boy receiving automated peritoneal dialysis. Pediatr Nephrol 2009;24:1253 4.
6. Kwon YJ, Lee DY. Corynebacterium aquaticum peritonitis in a patient on CAPD. Perit Dial Int 1997;17:98-9.
7. Morris AJ, Henderson GK, Bremner DA, Collins JF. Relapsing peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis due to Corynebacterium aquaticum. J Infect 1986;13:151-6.
8. Beckwith DG, Jahre JA, Haggerty S. Isolation of Corynebacterium aquaticum from spinal fluid of an infant with meningitis. J Clin Microbiol 1986;23:375-6.
9. Arslan S, Bozkurt H, Guducuoglu H, Berktas M, Caksen H, Kurtoglu MG, et al. Septicaemia and meningitis in an infant. J Paediatr Child Health 2001;37:414-5.
10. Tendler C, Bottone EJ. Corynebacterium aquaticum urinary tract infection in a neonate, and concepts regarding the role of the organism as a neonatal pathogen. J Clin Microbiol 1989;27:343-5.
11. Moore C, Norton R. Corynebacterium aquaticum septicaemia in a neutropenic patient. J Clin Pathol 1995;48:971-2.
12. D’Amico M, Mangano S, Spinelli M, Sala E, Vigano’ EF, Grilli R, et al. From the mailing list SIN: Epidemic of infections caused by ‘aquatic’ bacteria in patients undergoing hemodialysis via central venous catheters. G Ital Nefrol 2005;22:508-13.
13. Sulpher J, Desjardins M, Lee BC. Central venous catheter-associated Leifsonia aquatica bacteremia in a hemodialysis-dependent patient.Diagn Microbiol Infect Dis 2008;61:64-6.
14. Porte L, Soto A, Andrighetti D, Dabanch J, Braun S, Saldivia A, et al. Catheter-associated bloodstream infection caused by Leifsonia aquatica in a haemodialysis patient: A case report. J Med Microbiol 2012;61:868-73.
15. Larsson P, Lundin O, Falsen E. “Corynebacterium aquaticum” wound infection after high-pressure water injection into the foot. Scand J Infect Dis 1996;28:635-6.
16. Kaplan A, Israel F. Corynebacterium aquaticum infection in a patient with chronic granulomatous disease. Am J Med Sci 1988;296:57-8.
17. Han L, Lei JE, Wang X, Guo LT, Kang QY, He L, et al. Septicemia caused by Leifsonia aquatica in a healthy patient after retinal reattachment surgery. J Clin Microbiol 2013;51:3886-8.
18. Fischer RA, Peters G, Gehrmann J, Jurgens H. Corynebacterium aquaticum septicemia with acute lymphoblastic leukemia. Pediatr Infect Dis J 1994;13:836-7.
19. Corona A, Castelli A, Ballone E, Rech R, Colombo R, Ferraris S, et al. A case of septic shock secondary to Corynebacterium aquaticum bacteremia occurring in an HIV-infected patient attending a promiscuous thermal SPA. Minerva Anestesiol 2008;74:213-5.
20. Dempsey KE, Riggio MP, Lennon A, Hannah VE, Ramage G, Allan D, et al. Identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16S rRNA gene sequencing and by microbiological culture. Arthritis Res Ther 2007;9:R46.
21. Hung WL, Wade WG, Boden R, Kelly DP, Wood AP. Facultative methylotrophs from the human oral cavity and methylotrophy in strains of Gordonia, Leifsonia, and Microbacterium. Arch Microbiol 2011;193:407-17.
22. Tiago I, Chung AP, Veríssimo A. Bacterial diversity in a nonsaline alkaline environment: Heterotrophic aerobic populations. Appl Environ Microbiol 2004;70:7378-87.
23. Phelps W, Baughn R, Black HS. Passage of Corynebacterium aquaticum through membrane filters. In Vitro 1980;16:751-3.
24. Funke G, von Graevenitz A, Weiss N. Primary identification of Aureobacterium spp. isolated from clinical specimens as “Corynebacterium aquaticum”. J Clin Microbiol 1994;32:2686-91.
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