POSTERIOR SUBCAPSULAR CATARACT FOLLOWING PROLONGED ORAL STEROID USE FOR ALLERGIC CONJUNCTIVITIS: A CASE REPORT

Authors

  • AJAYI IYIADE ADESEYE Department of Ophthalmology, Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria.
  • OMOTOYE OLUSOLA JOSEPH Department of Ophthalmology, Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria.
  • OLULEYE TITILOPE TAIYE Department of Ophthalmology, Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria.

Keywords:

Cataract, Steroid, Treatment, Visual, Impairment

Abstract

Objective: We present a case of a 27-year-old female trader with a month history of bilateral painless progressive blurring of vision which was worse for distant vision after a 4-year daily use of oral prednisolone (10 mg) prescribed by a non-ophthalmologist. The conventional treatment for ocular allergy includes avoidance of allergens, topical antihistamines, mast cell stabilizers, topical corticosteroids, oral antihistamines, nonsteroidal anti-inflammatory drugs, and corticosteroids. However, inappropriate steroid use can be associated with undesirable complications.

Methods: A case report of a 27 year old female trader who presented with blurring of vision associated with glare at night. There was history of daily intake of oral prednisolone for 4 years for treatment of allergic conjunctivitis.

Results: Examination revealed posterior subcapsular cataract due to prolonged steroid use. Steroid was gradually tapered and withdrawn over a week and the patient was refracted with good visual improvement.

Conclusion: Steroids should be reserved for severe cases and when utilized should be used as pulsed or short course therapy after baseline examination by Ophthalmologists.

References

Deka M, Ahmed AB, Chakraborty J. Development, evaluation and characteristics of ophthalmic in situ gel system: A review. Int J Curr Pharm Res 2019;11:47-53.

Ono SJ, Abelson MB. Allergic conjunctivitis: Update on pathophysiology and prospects for future treatment. J Allergy Clin Immunol 2005;115:118-22.

Friedlaender MH. Ocular allergy. Curr Opin Allergy Clin Immunol 2011;11:477-82.

Bhosale NR, Kolte NS. Formulation development and evaluation of orally disintegrating tablet of orally disintegrating tablet of chlorpheniramine maleate by sublimation technique. Int J Pharm Pharm Sci 2019;11:28-36.

Fasasi MK, Kabir AA, Hamza BA, Richard AI, Sadiat SE, Abdulfattah I. Allergic conjunctivitis in a tertiary eye hospital, Nigeria. J Kathmandu Med Coll 2014;3:149-52.

Satyam SM, Adiga S, Chogtu B, Bairy KL, Pirasanthan R, Vaishnav RL. Effect of fucithalmic and sofinox eye drops on experimental allergic conjunctivitis in rats. Int J Pharm Pharm Sci 2014;6:458-60.

La Rosa M, Lionetti E, Reibaldi M, Russo A, Longo A, Leonardi S, et al., Allergic conjunctivitis: A comprehensive review of the literature. Ital J Pediatr 2013;39:18.

Comstock TL, Decoy HH. Advances in corticosteroids therapy for ocular inflammation: Loteprednol etabonate. Int J Inflam 2012;2012:789623.

James ER. The etiology of steroid cataract. J Ocul Pharmacol Ther 2007;23:403-20.

Jobling AI, Augusteyn RC. What causes steroid cataracts? A review of steroid-induced posterior subcapsular cataracts. Clin Exp Optom 2002;85:61-75.

Published

2019-11-01

How to Cite

AJAYI IYIADE ADESEYE, OMOTOYE OLUSOLA JOSEPH, & OLULEYE TITILOPE TAIYE. (2019). POSTERIOR SUBCAPSULAR CATARACT FOLLOWING PROLONGED ORAL STEROID USE FOR ALLERGIC CONJUNCTIVITIS: A CASE REPORT. Innovare Journal of Health Sciences, 7(6). Retrieved from https://innovareacademics.in/journals/index.php/ijhs/article/view/35797

Issue

Section

Case Study(s)