TY - JOUR AU - TAMIL SELVI I, AU - VIDHYA R, PY - 2019/01/01 Y2 - 2024/03/28 TI - PHYTOCHEMICAL ANALYSIS AND IN VITRO ANTIINFLAMMATORY ACTIVITY OF PERGULARIA DAEMIA (Forsk.) JF - Innovare Journal of Life Sciences JA - Innovare J Life Sci VL - 7 IS - 1 SE - Original Article(s) DO - UR - https://journals.innovareacademics.in/index.php/ijls/article/view/19160 SP - 1-5 AB - <p><strong>Objectives: </strong>The <em>in vitro </em>antiinflammatory activity of acetone and ethyl acetate extracts of <em>Pergularia deamia </em>leaf and stem<em>.</em></p><p><strong>Methods: </strong>The different parts of extracts were subjected to preliminary phytochemical screening as per the standard protocols. <em>In vitro </em>anti-inflammatory activities were evaluated by red blood cell (RBC) membrane stabilization, protein denaturation, and antiproteinase methods.</p><p><strong>Results: </strong>Preliminary phytochemical screening revealed that the presence of carbohydrates, phenol, tannins, flavonoids, alkaloids, steroids, and quinines in acetone extracts of plant. <em>In vitro </em>anti-inflammatory activities were tested using different concentrations of the extracts along with standard drug diclofenac sodium. The maximum anti-inflammatory activities were observed in ethyl acetate extracts of <em>P. daemia</em>. As the concentration of the extracts increased antiinflammatory activity also higher.</p><p><strong>Conclusion: </strong>The plant, therefore, might be considered as a natural source of RBC membrane stabilizers and prevention of protein denaturation, so it is substitute medicine for the management of inflammatory disorder.</p> ER -