CIRRHOTIC CARDIOMYOPATHY IN EGYPTIAN PATIENTS
Background: LiverÂ cirrhosis isÂ Â a health care problem inÂ EgyptÂ causedÂ by the high prevalence ofÂ hepatitis C virus (HCV)Â infection that affects 15-20 % of the populationÂ . Cirrhotic cardiomyopathy is the term used to describe a constellation of features indicative of abnormal heart structure and function in patients with cirrhosis. Aim of this study is to assess the pattern and the extent of cardiac affection in cirrhotic patients and its relation to the presence or absence of ascites. Materials Â and methods: This study was carried out on 70 patients with liver cirrhosis and 30 healthy controls. All persons were subjected to careful history & physical examination, laboratory investigations, abdominal ultrasonography ,and echocardiography. Results:Â Â left ventricle end diastolic diameter was significantlyÂ increased in cirrhotic patients withÂ ascites (5.40Â±0.58)Â and without ascites ((5.31Â±0.51), compared to the control group (4.52Â±0.58) (p<0.05), . left ventricle end systolic diameter wasÂ Â Â Â Â increased in cirrhotic patients withÂ ascites (3.57Â±2.2)Â and without ascites (3.46Â±3.1), without ascites (3.18Â±2.5)but the difference was statistically non significantÂ Â Â (p > 0.05).Â Â Left atrium diameter & Right ventricular end diastolic diameter were significantly increased in cirrhotic patients compared to the control group (p<0.05Â TheÂ pulmonary artery pressureÂ was elevated in cirrhotic patients compared to the control group .. Conclusion:Â In the present study ptient with Liver cirrhosis were Â associated with significant enlargement of cardiac chambers and diastolic dysfunction compared to the control group speciallyÂ Â inÂ the presence of ascites.
dr Maher El amir