HISTOLOGICAL VARIANCES OF MORINGA OLIFERA ON THE KIDNEY OF ADULT WISTAR RATS

Authors

  • ADETUNJI OPEYEMI ADEBOLA Department of Anatomy, School of Basic Medical Sciences, Benjamin S. Carson (SNR.) College of Medicine, Babcock University, Ilisan-Remo, Ogun State, Nigeria.
  • OYEWO OLUWATOYIN Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
  • ADETUNJI IYABODE TOYIN Department of Pure and Applied Biology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
  • NWOBI NNENA LINDA Department of Chemical Pathology, School of Pre-Clinical Sciences, Babcock University, Ogun State, Nigeria.

DOI:

https://doi.org/10.22159/ijms.2021.v9i3.41144

Keywords:

Crude Aqueous Extract, Moringa Oleifera Leaves, Kidney

Abstract

Aim and Objectives: Demonstrating the exact quantity of Moringa oleifera (MO) that will cure any hepatocyte diseases and the one that can harm the hepatocytes of the Adult Wistar rats.

Methods: Twenty (20) adult Wistar rats (both sex) were used for the study (caged based on same sex to avoid mating and pregnancy) and were randomly assigned into four groups (n=5); A-Control, B-250 mg/body weight (BW) of MO, C-500 mg/BW of MO, and D-750 mg/BW of MO orally.

Result: The crude aqueous extract of MO Lam, shows insignificant increased in BW at the 1st week of administration which latter dropped little by little doing the weeks of the administration in groups (B, C, and D) rats, by comparing (p<0.05) to the control group after MO administration, the organ (Kidneys) shows a significant difference between the kidneys (left and right kidneys) in relation to the control group rats. MO increases the weight of the animals morphologically by comparing the weight of the animals before and after administration. Histological sections shows a normal Glomerulli, Peri-Glomerular Space, Convoluted Tubules, and Interstitium, after administration of the Crude Aqueous Extract of MO lame in terms with the control group rats.

Conclusion: MO is a good herb that has no damage effect on the body and hepatocytes but of more beneficial.

References

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Published

01-05-2021

How to Cite

ADEBOLA, A. O., OLUWATOYIN, O., TOYIN, A. I., & NNENA LINDA, N. (2021). HISTOLOGICAL VARIANCES OF MORINGA OLIFERA ON THE KIDNEY OF ADULT WISTAR RATS. Innovare Journal of Medical Sciences, 9(3), 36–38. https://doi.org/10.22159/ijms.2021.v9i3.41144

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Original Article(s)