A COMPREHENSIVE REVIEW OF CANDIDIASIS
Keywords:Candidiasis, Candida Albicans, Fluconazole, In vivo model.
Candidiasis is a fungal infection caused by the genus Candida. It is otherwise called moniliasis, thrush, and candidosis. Candida albicans is the most one to cause an infection in humans and other species such as Candida auris, Candida tropicalis, Candida glabrata, Candida parapsilosis, C. parapsilosis, and Candida lusitaniae. It is categorized into oral candidiasis, invasive candidiasis, vulvovaginal, and genital candidiasis. In general, Candida yeasts are present in the human body and their growth is limited by the human immune system. When an imbalance, colonization of Candida occurs finally leads to an infection. It is mainly affected in immune compromised patients followed by risk factors such as diabetes, stem cell transplantation, organ transplantation, and prolonged use of antibiotics, and steroids. It can be diagnosed to overcome this infection by direct examination of smear, culture, and biopsy. Fluconazole is the first line drug to treat candidiasis and Amphotericin-B, Caspofungin, Voriconazole also used.
Rafiq NB. Candidiasis. Treasure Island, FL: StatPearls: StatPearls Publishing; 2021.
Lynch DP. Oral Candidiasis: History, class, and clinical presentation. Oral Surg Oral Med Oral Pathol 1994;78:189-93.
Singh A, Verma R, Murari A, Agrawal A. Oral Candidiasis: An overview. J Oral Maxillofac Pathol 2014;18:81-5.
Zarrin M, Mahmoudabadi AZ. Invasive candidiasis; a review article. Jundishapur J Microbiol 2009;2:1-6.
Keighley C, Cooley L, Morris AJ, Ritchie D, Clark JE, Boan P, et al. Consensus guidelines for the diagnosis and management of invasive candidiasis in haematology, oncology and intensive care settings, 2021. Intern Med J 2021;51:89-117.
Krishnan PA. Fungal infections of the oral mucosa. Indian J Dent Res 2012;23:650-9.
Sravanthi V, Kalyan D, Kumar MV, Meher CP, Finny GJ. A review on candidiasis: Types and medications. Pharma Tutor 2014;2:36-45.
Lakshmi L, Anithalekshmi MR, Abraham L, Nair MM, Aniyan N, Nair NM, et al. Oral candidiasis-review. Int J Res Pharm Nano Sci 2015;4:409-17.
Colombo AL, Guimarães T, Camargo LF, Richtmann R, de Queiroz- Telles F, Salles MJ, et al. Brazilian guidelines for the management of candidiasis-a joint meeting report of three medical societies: Sociedade brasileira de infectologia, sociedade paulista de infectologia and sociedade brasileira de medicina tropical. Braz J Infect Dis 2013;17:283-312.
Arfiputri DS, Hidayati AN, Handayani S, Ervianti E. Risk factors of vulvovaginal candidiasis in dermato-venereology outpatients clinic of Soetomo general hospital, Surabaya, Indonesia. Afr J Infect Dis 2018;12:90-4.
Martins N, Ferreira IC, Barros L, Silva S, Henriques M. Candidiasis: Predisposing factors, prevention, diagnosis and alternative treatment. Mycopathologia 2014;177:223-40.
Pappas PG, Rex JH, Sobel JD, Filler SG, Dismukes WE, Walsh TJ, et al. Guidelines for treatment of candidiasis. Clin Infect Dis 2004;38:161-89.
Singh G, Raksha A, Urhekar AD. Candidal infection: Epidemiology, pathogenesis and recent advances for diagnosis. Bull Pharma Med Sci 2013;1:1-8.
Segal E, Frenkel M. Experimental in vivo models of candidiasis. J Fungi (Basel) 2018;4:21.
Nagaraj T, Kongbrailatpam S, Mumtaz S, Mohiyuddin YS. Oral erythematous candidiasis: A case report. Int J Med Dent Case Rep 2020;7:1-4.
Riad A, Gomaa E, Hockova B, Klugar M. Oral candidiasis of COVID‐19 patients: Case report and review of evidence. J Cosmetic Dermatol 2021;20:1580-4.
Hani U, Shivakumar HG, Vaghela R, Osmani RA, Shrivastava A. Candidiasis: A fungal infection--current challenges and progress in prevention and treatment. Infect Disord Drug Targets 2015;15:42-52.
Akpan A, Morgan R. Oral candidiasis. Postgrad Med J 2002;78:455-9.
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