https://innovareacademics.in/journals/index.php/ijms <p>Innovare Journal of Medical Sciences had started in April 2013 is a peer-reviewed, bimonthly (Onward April 2016), open access Journal. The Journal publishes original research in Medical Sciences and its scope includes work that relate with <strong>Medicine, dentistry, nursing and allied health sciences, pharmacy, pathology, anatomy, physiology, pharmacology, toxicology, surgery and physiology, Orthopedics or Bones Nutrition, Ophthalmology, Wounds &amp; injuries, Infectious diseases, Global health, Anesthesia, Analgesia and pain, Cardiovascular diseases</strong>. The Journal publishes original research work either as an Original article or as a Short Communication. Case studies/reports, Review Articles are also considered for publication in the field of Medical Sciences.</p> <p><strong>Abstracting and Indexing-&nbsp;</strong>OAI, <a href="http://scholar.cnki.net/webpress/brief.aspx?dbcode=SJQA" target="_blank" rel="noopener">CNKI (China Knowledege Resource Integrated Database)</a>, LOCKKS, Open J-Gate, Google Scholar, OCLC (World Digital Collection Gateway), UIUC</p> Innovare Academic Sciences Pvt Ltd en-US Innovare Journal of Medical Sciences 2321-4406 https://innovareacademics.in/journals/index.php/ijms/article/view/52850 <p><strong>Objectives: </strong>To evaluate of anti-cataract potential of <em>Scaevola taccada </em>in <em>ex vivo </em>Goat eye models.</p> <p><strong>Methods: </strong>Goat eye lenses separated into five groups were incubated in synthetic aqueous humor culture, added by streptomycin of 0.1 mg/mL was at 37°C for 72 h. Group I use as the normal control. In Group II (disease control), the lenses were added by 1 M glucose. The lenses in Group III (standard control) were incubated in an aqueous humor medium with 1 M glucose added by 500 μg/mL of Gallic acid. The lenses in Group IV (Test Group) were incubated in aqueous humor medium with 1 M glucose added by 500 μg/mL of extract of <em>S. taccada</em>. MDL levels and catalase activity were measured by using ultraviolet Spectroscopy. Statistical analysis of evaluation parameters was conducted using analysis of variance and <em>post hoc </em>Tuckey test.</p> <p><strong>Results: </strong>As a part of the study, in malondialdehyde (MDA) level estimation, our test drug has a low MDA level as compared to the disease control. Hence, it may be acting as an anti-cataract. In total protein estimation, the test drug has a higher amount of total protein in comparison with others. By analyzing catalase activity, Catalase activity data revealed that the test drug is having high catalase activity as compared to the standard control group. Hence, we conclude that it works as an anti-cataract.</p> <p><strong>Conclusion: </strong>The study carried out clearly revealed that <em>S. taccada </em>(Bhadrax) has the potential for anti-cataract activity. This hypothesis was supported by finding such total protein level, MDA level, and catalase activity.</p> GALATHIYA MEET SAVANKUMAR CHHATROLA BHARGAV KAMANI TEJAS GANATRA Copyright (c) 2024 GALATHIYA MEET, SAVANKUMAR CHHATROLA, BHARGAV KAMANI, TEJAS GANATRA http://creativecommons.org/licenses/by/4.0 2024-11-01 2024-11-01 1 5 10.22159/ijms.2024v12i6.52850