• Wafa Tadrent
  • Khaldoun Bachari
  • Zahia Kabouche Université des frères Mentouri-Constantine, Département de chimie, Laboratoire d’Obtention de Substances Thérapeutiques, 25000 Constantine, Algeria


Anthemis nobilis L, Anthemis mixta L, chemical composition, antibacterial activity


Objective: To evaluate the chemical composition of essential oils from aerial parts of Anthemis nobilis (An) and Anthemis mixta L (Am). and investigate their antibacterial property.

Methods: The essential oils were isolated by hydro distillation and analyzed by GC and GC-MS. The disc diffusion and Agar dilution methods were used to screen the antibacterial activity against referenced and/or clinically isolated (HS) strains of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella enterica, Klebsiella pneumonia and Shighuelle sonnei.

Results: The main constituents of An essential oil were 3-methyl-2-buten-1-yl cyclopropane carboxylate (29.3%), vinyl-2,2-dimethylbutanoate (24.2%), glycidyl methacrylate (9.9%), 2-methylbutyl-2-mehylbutyrate (9.1%), isobutyl isobutyrate (7.8%) and 3,3,4-trimethylhexane (6.2%), while Am essential oil was mainly characterized by α-thujone (51.8%), β-thujone (14.6%), borneol (7.3%) and 3-hexen-1-ol (4.9%). An and Am essential oils exhibited the best antibacterial activity against the following strains of Escherichia coli ATCC 25922 (25±1.20, 32±1.00 mm), Pseudomonas aeruginosa ATCC 27853 (23±0.87, 32±0.76 mm) and Staphylococcus aureus ATCC 43300 (21±1.44, 25±1.24 mm inhibition zone diameters, respectively). Minimum inhibitory concentration (MICs) values of these oils were ranged from 32-128µg/ml.

Conclusion: From this study, it can be concluded that the chemical composition of the essential oils was related to their antibacterial activity.

Keywords: Anthemis nobilis L., Anthemis mixta L., Chemical composition, Antibacterial activity


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How to Cite

Tadrent, W., K. Bachari, and Z. Kabouche. “COMPARATIVE COMPOSITIONS AND ANTIBACTERIAL ACTIVITY OF THE ESSENTIAL OILS OF ANTHEMIS NOBILIS L. AND ANTHEMIS MIXTA L. (ASTERACEAE)”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 7, July 2016, pp. 457-9,



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