A CASE REPORT ON TAKAYASU’S ARTERITIS


Sharmila Mohan, R Lakshmi

Abstract


Takayasu’s arteritis (TA) is a rare large-vessel vasculitis that affects large arteries, mainly the aorta and its branches. It is also called a pulseless disease because of diminished or absent pulses in the upper extremities of the patient. The coronary, pulmonary and renal arteries are also affected in the progression of the disease. The prevalence of the disease is more in Asian countries and it has unknown etiopathogenesis. Here we discuss a case of TA in a 15 y old girl who was admitted with moderate LV dysfunction. The diagnosis was carried out from the results of CT aortogram which showed stenosis of right common carotid, left subclavian, left vertebral artery, right renal artery and lower lobe pulmonary arteries and other clinical examinations. Treatment was initiated with methylprednisolone and cyclophosphamide along with symptomatic treatment. But the disease progressed with the development of complications like peripheral leg ulcers. The patient was initiated palliative care in view of altered sensorium and severe LV dysfunction, but the patient succumbed to a sudden cardiac arrest. Early identification and initiation of aggressive treatment can help in symptom-free survival.


Keywords


Takayasu’s arteritis, Vasculitis, Coronary artery

| PDF | HTML |

References


Saab F, Giugliano RP, Giugliano GR. Takayasu arteritis in a young woman A 4-year case history. Tex Heart 2009;36:470–4.

Johnston SL, Lock RJ, Gompel MM. Takayasu arteritis: a review. J Clin Pathol 2002;55:481–6.

Jain S, Pondaiah SK. Takayasu's arteritis: a review of epidemiology and etiopathogenesis. Indian J Rheumatol 2015;10:S22–9.

Das D, Mondal KK, Ray B, Chakrabarti A. A case of unusual presentation of Takayasu's arteritis. Indian J Ophthalmol 2010;58:148–50.

Al-Bishri J. Takayasu’s arteritis: a review article. Br J Med Med Res 2013;3:811-20.

Khan MAM, Banoo H. A case report of takayasu’s arteritis. Med Today 2012;24:79-81.

Kim HJ, Suh DC, Kim JK, Kim SJ, Lee JH, Choi CG, et al. Correlation of neurological manifestations of Takayasu arteritis with cerebral angiographic findings. Clin Imaging 2005;29:79-85.

Park MC, Park YB, Jung SY, Lee KH, Lee SK. Anti-endothelial cell antibodies and antiphospholipid antibodies in Takayasu's arteritis: correlations of their titers and isotype distributions with disease activity. Clin 2006;24(2, Suppl 41):S10-6.

Moriwaki R, Noda M, Yajima M, Sharma BK, Numano F. Clinical manifestations of Takayasu arteritis in India and Japan—new classification of angiographic findings. Angiology 1997;48:369–79.

Keser G, Direskeneli H, Aksu K. Management of Takayasu arteritis: a systematic review. Rheumatology (Oxford) 2014;53:793-801.




About this article

Title

A CASE REPORT ON TAKAYASU’S ARTERITIS

Keywords

Takayasu’s arteritis, Vasculitis, Coronary artery

DOI

10.22159/ijpps.2017v9i3.15034

Date

03-02-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 9, Issue 3, 2017 Page: 296-297

Online ISSN

0975-1491

Statistics

89 Views | 61 Downloads

Authors & Affiliations

Sharmila Mohan
Department of Pharmacy Practice, Amrita School of Pharmacy, Kochi, Amrita Vishwa Vidyapeetham, Amrita University, India
India

R Lakshmi
Department of Pharmacy Practice, Amrita School of Pharmacy, Kochi, Amrita Vishwa Vidyapeetham, Amrita University, India
India


Article Tools



Refbacks

  • There are currently no refbacks.