RELATIONSHIP OF BODY FAT PERCENTAGE AND APO B/APO A-1 RATIO AS CARDIOVASCULAR RISK MARKER IN RURAL ADULTS OF YOGYAKARTA INDONESIA

Fenty .; Aris Widayati; Phebe Hendra

doi:10.22159/ijpps.2017v9i2.15864

Authors

Fenty . Faculty of Pharmacy Universitas Sanata Dharma Yogyakarta, Indonesia
Aris Widayati Faculty of Pharmacy Universitas Sanata Dharma Yogyakarta, Indonesia
Phebe Hendra Faculty of Pharmacy Universitas Sanata Dharma Yogyakarta, Indonesia

DOI:

https://doi.org/10.22159/ijpps.2017v9i2.15864

Keywords:

Body Fat Percentage, apo Bapo A-1 ratio, relationship

Abstract

Objective: Prevalence of obesity and cardiovascular disease has increased in both urban and rural areas Indonesia. High body fat percentage (BF%) is associated with a high cardio metabolic risk. The apolipoproteins (Apo) B/Apo A-1 ratio is a better risk predictor for cardiovascular disease. This study aimed to explore the relationship of BF% and Apo B/Apo A-1 ratio among rural adults in Yogyakarta Indonesia.

Methods: This cross-sectional study included 40 men and 62 women (40-60 y old). Those who had cardiometabolic diseases, edema or currently taking cardio metabolic medicines were excluded. Information about sociodemographic details was obtained by using a self-administerd questionnaire. The questionnaire also assessed smoking status, reproductive history and medical history. Anthropometric measurement, apo B, Apo A-1, fasting blood glucose and blood pressure were measured.

Results: The prevalence of high BF% was 12.7% and 6.9% in men and women, respectively. There was negative correlation between BF% and apo A-1 and positive correlation between BF% and apo B as well as BF% and apo B/apo A-1 ratio. A significant weak correlation was observed between BF%-apo B/apo A-1 ratio in women (r: 0.280; p: 0.027).

Conclusion: BF% is associated with apo B/apo A-1 ratio among women adults in rural area of Yogyakarta Indonesia findings support the importance of using BF% to predict cardiovascular disease in rural area.

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References

Sandjaja, Sudikno. Prevalence of overweight and obesity in adults Indonesia. Gizi Indonesia 2005;31:1-7.

Ministry of Health Republic of Indonesia. Riset Kesehatan Dasar Indonesia Jakarta 2013;5:258-60.

Popkin BM. Does global obesity represent a global public health challenge? Am J Clin Nutr 2011;93:232-3.

Widjaja FF, Santoso LA, Barus NRV, Pradana GA, Estetika C. Prehypertension and hypertension among young indonesian adults at a primary health care in a rural area. Med J Indian 2013;22:39-45.

Fenty, Widayati A, Virginia DM, Hendra P. Metabolic syndrome among adults in rural areas. Indonesian J Clin Pathol Med Laboratory 2016;22:254-7.

World Health Organization. Obesity and Overweight, Fact Sheet N Â°311; 2015. Available from: http://www.who.int/ mediacentre/factsheets/fs311/en/ [Last accessed on 10 Feb 2016].

Lavie CJ, Milani RV, Ventura HO. Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J Am Coll Cardiol 2009;53:1925-32.

Jiang J, Ahn J, Huang WY, Hayes RB. Association of obesity with cardiovascular disease in the PLCO trial. Prev Med 2013;57:60-4.

Valentino G, Bustamante MJ, Orellana L, Kramer V, Duran S, Adasme M, et al. Body fat and its relationship with clustering of cardiovascular risk factor. Nutr Hosp 2015;31:2253-60.

WHO expert consultation. Appropiate body mass index for asian population and its implication for policy and intervention strategies. Lancet 2004;363:157-63.

Deurenberg-Yap M, Chew S, Deurenberg P. Elevated body fat percentage and cardiovascular risks at low body mass index levels among Singaporean Chinese, Malays, and Indians. Obes Rev 2002;3:209-15.

Deurenberg-Yap M, Schmidt G, van Staveren WA, Deurenberg P. The paradox of low body mass index and high body fat percentage among Chinese, Malays and Indians in Singapore. Int J Obesity Related Metab Disorders 2000;24:1011-7.

Kim JY, Han SH, Yang BM. Implication of high-body-fat percentage on cardiometabolic risk in middle aged, healthy, normal weight adults. Obesity 2013;21:1571-7.

Dawar R, Gurtoo A, Singh R. Apo B/Apo A1 ratio is statistically the best predictor of myocardial infarction compared to other lipid ratios. Int J Pharma Biosci 2010;1:1-8.

Walldius, Jungner I, Holme I, Aastveit AH, Kolar W, Steiner E. High apolipoprotein B, low apolipoprotein A1, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet 2001;358:2026-33.

Kaneva AM, Potolitsyna NN, Bojko ER, Odland JO. The apolipoprotein B/apolipoprotein A-1 ratio as a potential marker of plasma atherogenicity. Dis Markers 2015. http://dx.doi.org/10.1155/2015/591454.

Sailaja AK. An overall review on obesity and its related disorders. Innovare J Life Sci 2015;3:1-3.

National Health and Nutrition Examination Survey (NHANES), Antropometry Procedures Manual, CDC, U. S.; 2007. p. 1-1, 1-2.

Hoeger WWK, Hoeger SA. Principles and Labs for Fitness and Wellnes. 12th Ed. Wadsworth Cengage Learning, USA; 2014. p. 126, 132, 142.

Shakibaee A, Faghihzadeh S, Alishiri GH, Ebrahimpour Z, Faradjzadeh S, Sobhani V, et al. How accurate are the anthropometry equations in Iranian military men in predicting body composition? Asian J Sports Med 2015;6:e23206.

Esmat T. Measuring and Evaluating Body Composition; 2016. Available from: http://www.acsm.org/public-information/ articles/2016/10/07/measuring-and-evaluating-body-composition. [Last accessed on 10 Feb 2016]

Rahl RV. Physical Activity and Health Guidelines Recommendations for Various Ages, Fitness level and Condition From 57 Authoritative Sources; 2010. p. 252.

Habib SS. Body mass index and body fat percentage in assessment of obesity prevalence in Saudi Adults. Biomed Environ Sci 2013:26:94-9.

Amin F, Fatima SS, Islam N, Gilan AH. Prevalence of obesity and overweight, its clinal markers and associated factors in a high risk South-Asian population. BMC Obese 2015;2:16.

Ho-Pham LT, Lai TQ, Nguyen MTT, Nguyen TV. Relationship between body mass index and percent body fat in vietnamese: implications for the diagnosis of obesity. PLoS One 2015;10:e0127198.

Su TT, Amiri M, Hairi FH, Thangiah N, Dahlui M, Majid HA. Body composition indices and predicted cardiovascular disease risk profile among urban dwellers in Malaysia. BioMed Res Int 2015;201-7. http://dx.doi.org/10.1155/2015/174821

Myint PK, Kwok CS, Luben RN, Wareham NJ, Khaw KT. Body fat percentage, body mass index and waist-to-hip ratio, as predictors of mortality and cardiovascular disease. Heart 2014;100:1613-9.