PHYTOCHEMICAL ANALYSIS OF SECONDARY METABOLITES OF SATUREJA HORTENSIS L.

Authors

  • Mariya Shanaida Department of Pharmacognosy with Medical Botany, I. Horbachevsky Ternopil State Medical University, Ternopil, 46001, Ukraine
  • Iryna Ivanusa Department of Pharmaceutical Chemistry, I. Horbachevsky Ternopil State Medical University, Ternopil, 46001, Ukraine
  • Ivanna Kernychna Department of Pharmacognosy with Medical Botany, I. Horbachevsky Ternopil State Medical University, Ternopil, 46001, Ukraine

DOI:

https://doi.org/10.22159/ijpps.2017v9i2.15923

Keywords:

Satureja hortensis, Essential Oil, Tannins, HPLC, GC-MS

Abstract

Objective: The present study was designated to analyse the essential oils and tannins as important secondary metabolites of the aerial part of Satureja hortensis.

Methods: The chemical composition of S. hortensis herb was investigated using high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS). The essential oil was obtained by hydrodistillation method.

Results: The essential oil yield in the aerial part of S. hortensis was 1.61%. GC-MS analysis of the essential oils identified the presence of 29 components. Carvacrol (76.16%), as the main component of essential oils, belongs to the group of aromatic compounds. Eight tannin components identified by HPLC and epigallocatechin (130.91х10-2%) are prevalent among them.

Conclusion: S. hortensis was found to possess considerable amount of phytoconstituents such as essential oils and tannins. The results of this research will help to study pharmacological properties of the investigated plant and to prevent possible adulteration with other plants.

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References

Trease and Evans' Pharmacognosy. 16th Edition. Saunders Ltd; 2009. p. 616.

Crozier A, Clifford M, Ashihara H. Plant secondary metabolites: occurrence, structure and role in the human diet. Oxford, Blackwell Publishing Ltd; 2006. p. 384.

Compean KL, Ynalvez RA. Antimicrobial activity of plant secondary metabolites: a review. Res J Med Plant 2014;8:204–13.

Vaiciulyte V, Butkiene R, Loziene K. Effects of meteorological conditions and plant growth stage on the accumulation of carvacrol and its precursors in Thymus pulegioides. Phytochemistry 2016;128:20–6.

Poonkodi K. The chemical composition of essential oil of Ocimum basilicum L. (basil) and its biological activities–an overview. J Crit Rev 2016;3:56–62.

Wink W. Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective. Phytochemistry 2003; 64:3–19.

Momtaz S, Abdollahi M. An update on the pharmacology of Satureja species; from antioxidant, antimicrobial, antidiabetes and anti-hyperlipidemic to reproductive stimulation. Int J Pharmacol 2010;6:346–53.

Pharmacopoeia Europaea. 8th edition; 2014. p. 8.0–8.2.

Saeidina S, Gohari Ð, Manayi Ð, Kourepaz-Mahmoodabadi Ðœ. Satureja: ethnomedicine, phytochemical diversity and pharmacological activities. Springer Briefs in Pharmacology and Toxicology; 2016. p. 31–65.

Bezic N, Samanic I, Dunkic V, Besendorfer V, Puizina J. Essential oil composition and internal transcribed spacer (ITS) sequence variability of four south-croatian Satureja species (Lamiaceae). Molecules 2009;14:925–38.

Shanayda MI, Sira LM, Minaieva AO. The morphological and anatomical structure of Satureja hortensis L. herb. ScienceRise 2016;4:30–7.

Kolopenyuk M. Agro-climatic zoning of Ternopil region. Ternopil Encyclopedic Dictionary: Ternopil, Zbruch; 2004. р. 696.

Adams RP. Identification of essential oils components by gas chromatography-quadrupole mass spectroscopy. Allured Publishing Corporation; 2001. p. 455.

Sensitive determination of catechins in tea by HPLC. Thermo Scientific DIONEX Corporation an; 2011. Available from: http://www.dionex.com/en-us/webdocs/110783-AN275-HPLC-Catechins-Tea-19May2011-LPN2799.pdf. [Last accessed on 20 Sep 2016].

Baser K. Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils. Curr Pharm Des 2008;14:3106–19.

Staszek D, Orlowska M, Waksmundzka-Hajnos M, Sajewicz M, Kowalska T. Marker fingerprints originating from TLS and HPLC for selected plants from the Lamiaceae family. J Liquid Chromatogr 2013;36:2463–75.

Zielinska S, Matkowski A. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochem Rev 2014;13:391–416.

Sahin F, Caraman І. Evaluation of antimicrobial activities of Satureja hortensis L. J Ethnopharmacol 2003;87:61–5.

Sokovic M, Glamoclija J, Marin D. Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. Molecules 2010;15:7532–46.

Thaniarasu R, Senthil KT, Abubacker MN, Rao MV. Preliminary phytochemical screening and evaluation of antibacterial activity of different solvent extracts of Plectranthus bourneae gamble (Lamiaceae). Asian J Pharm Clin Res 2015;8:79–82.

Dewick PM. Medicinal natural products: a biosynthetic approach. United Kingdom: John Wiley and Sons; 2009. p. 187–97.

Hajhashemi V, Zolfaghari B, Yousefi A. Antinociceptive and anti-inflammatory activities of Satureja hortensis seed essential oil, hydroalcoholic and polyphenolic extracts in animal models. Med Princ Pract 2012;21:178–88.

Gautam RK, Singh RK, Karchuli M. Evaluation of nephroprotective activity of Mentha arvensis in cisplatin-induced nephrotoxicity. Asian J Pharm Clin Res 2014;7:188–91.

Hanganu D, Vlase L, Filip L, Sand C, Mirel S, Indrei L. The study of polyphenolic compounds from Melissa officinalis L. (Lamiaceae). Farmacie 2008;112:525–9.

Chung KT, Wong TY, Wei CI, Huang YW, Lin Y. Tannins and human health: a review. Crit Rev Food Sci Nutr 1998;38:421–64.

Khomdram S, Potsangbam K. Polyphenolic Ñompounds and free radical scavenging activity in eight Lamiaceae herbs of Manipur. Not Sci Biol 2011;3:108–13.

Vlase L, Benedec D, Hanganu D, Damian G, Csillag I, Sevastre B, et al. Evaluation of antioxidant and antimicrobial activities and phenolic profile for Hyssopus officinalis, Ocimum basilicum and Teucrium chamaedrys. Molecules 2014;19:5490–507.

Yesiloglu Y, Sit L, Kilic I. In vitro antioxidant activity and total phenolic content of various extracts of Satureja hortensis L. collected from Turkey. Asian J Chem 2013;25:8311–6.

Published

01-02-2017

How to Cite

Shanaida, M., I. Ivanusa, and I. Kernychna. “PHYTOCHEMICAL ANALYSIS OF SECONDARY METABOLITES OF SATUREJA HORTENSIS L”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 9, no. 2, Feb. 2017, pp. 315-8, doi:10.22159/ijpps.2017v9i2.15923.

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Section

Short Communication(s)