PHARMACOEPIDEMIOLOGICAL SURVEY ON THE USE OF COSTUS PICTUS (INSULIN PLANT) IN CENTRAL KERALA


Biji Joseph, Sherina Jacob, Nishant Kumar Gupta, Binu T. Kuruvilla, Merina Benny, Benny Antony

Abstract


Objective: Costus pictus commonly known as spiral ginger or insulin plant is grown in gardens as ornamental plant especially in Kerala and used to control sugar levels. The objective of the present survey was to collect information on the use of this plant as a control measure for diabetes mellitus in a community in central Kerala.

Methods: The study was conducted with the help of a semi-structured questionnaire. The questionnaire broadly included questions about knowledge of insulin plant, its use, quantity and frequency of use, the relation of plant material consumption with food intake, effects related to blood sugar level and other symptoms, any discomfort or complications after use among diabetic and normal people. The data obtained was quantitatively transferred to an excel sheet and statistical analysis was carried out.

Results: From the survey, it can be inferred that Costus pictus is widely used to normalise their sugar level. People who are using insulin plant have not done any species identification scientifically. Due to lack of knowledge and difficulty in identification (especially in the non-flowering season), many people are using Costus speciosus without knowing its adverse effects and allergic reactions.

Conclusion: From the survey, it can be concluded that Costus pictus is widely used in some part of the community in Kerala, to normalize their sugar level. It is warranted to increase the awareness in the community about different species of Costus plant and adverse effects associated with similar species.


Keywords


Costus pictus, insulin plant, pharmacoepidemiological survey, diabetes

| PDF | HTML |

References


Baily CJ, Flatt PR. Antidiabetic drugs, new developments. Indian Biotech 1986;6:139–42.

Subramoniam A, Pushpangadan P, Rajasekaran S, Evans DA, Latha PG, Valsaraj R. Effects of Artemisia pallens Wall on blood glucose levels in normal and alloxan-induced diabetic rats. J Ethnopharmacol 1996;50:13–7.

Mukherjee PK, Saha K, Pal M, Saha BP. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. J Ethnopharmacol 1997;58:207–13.

Benny M. Insulin plant in gardens. Nat Prod Radiance 2004;3:349-50.

Martinez M. Las plantas medicinales de mexico. 6th ed. Mexico: Andres Botas; 1996.

Hegde PK, Rao HA, Rao PN. A review on Insulin plant (Costus igneus Nak). Pharmacog Rev 2014;8:67–72.

Jothivel N, Ponnusamy SP, Appachi M, Singaravel S, Rasilingam D, Deivasigamani K, et al. the Anti-diabetic activity of methanol extract of Costus pictus D Don in alloxan-induced diabetic rats. J Health Sci 2007;53:655–63.

Benny M, Antony B, Santhakumari G, Sheeba V. Antihyperglycemic effect of Costus pictus in alloxan induced diabetic rats. Indian J Nat Prod 2006;22:8-12.

Suganya S, Narmadha R, Gopalakrishnan VK, Devaki K. Hypoglycemic effect of Costus pictus D. Don on alloxan induced type 2 diabetes mellitus in albino rats. Asian Pac J Trop Dis 2012;2:117–23.

Meléndez-Camargo ME, Castillo-Nájera R, Silva-Torres R, Campos-Aldrete ME. Evaluation of the diuretic effect of the aqueous extract of Costus pictus D Don in rat. Proc West Pharmacol Soc 2006;49:72–4.

Annadurai RS, Jayakumar V, Mugasimangalam RC, Katta M, Anand S. Next generation sequencing and de novo transcriptome analysis of Costus pictus D. Don, a non-model plant with potent anti-diabetic properties. BMC Genomics 2012;13:663.

Sidhu AK, Wani SJ, Tamboli JP, Patil SN. In vitro evaluation of anti-diabetic activity of leaf and callus extracts of Costus pictus. Int J Sci Res 2014;3:1622-5.

Shilpa K, Sangeetha KN, Muthusamy VS, Sujatha S, Lakshmi BS. Probing key targets in insulin signaling and adipogenesis using a methanolic extract of Costus pictus and its bioactive molecule, methyl tetracosanoate. Biotechnol Lett 2009;31:1837-41.

Gireesh G, Thomas SK, Joseph B, Paulose CS. Antihyperglycemic and insulin secretory activity of Costus pictus leaf extract in streptozotocin induced diabetic rats and in in vitro pancreatic islet culture. J Ethnopharmacol 2009;123:470–4.

Jayasri MA, Radha A, Mathew TL. α-amylase and α-glucosidase inhibitory activity of Costus pictus D. DON in the management of diabetes. J Herb Med Toxicol 2009;3:91-4.

Aruna A, Nandhini SR, Karthikeyan V, Bose P. Comparative in vitro antioxidant screening of methanolic extract of Costus pictus and its silver nanoparticles. Int J Pharm Sci Drug Res 2014;6:334-40.

De Smet PA. An introduction to herbal pharmacoepidemiology. J Ethnopharmacol 1993;38:197-208.




About this article

Title

PHARMACOEPIDEMIOLOGICAL SURVEY ON THE USE OF COSTUS PICTUS (INSULIN PLANT) IN CENTRAL KERALA

Keywords

Costus pictus, insulin plant, pharmacoepidemiological survey, diabetes

DOI

10.22159/ijpps.2017v9i4.16492

Date

14-02-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 9, Issue 4, 2017 Page: 73-77

Online ISSN

0975-1491

Statistics

77 Views | 50 Downloads

Authors & Affiliations

Biji Joseph
Research and Development Laboratory, Arjuna Natural Extracts Ltd., Nalam Mile, Kulakadu Road, Erumathala, Keezhmad, Kerala 683112, India

Sherina Jacob
Research and Development Laboratory, Arjuna Natural Extracts Ltd., Nalam Mile, Kulakadu Road, Erumathala, Keezhmad, Kerala 683112, India

Nishant Kumar Gupta
Research and Development Laboratory, Arjuna Natural Extracts Ltd., Nalam Mile, Kulakadu Road, Erumathala, Keezhmad, Kerala 683112, India

Binu T. Kuruvilla
Research and Development Laboratory, Arjuna Natural Extracts Ltd., Nalam Mile, Kulakadu Road, Erumathala, Keezhmad, Kerala 683112, India

Merina Benny
Research and Development Laboratory, Arjuna Natural Extracts Ltd., Nalam Mile, Kulakadu Road, Erumathala, Keezhmad, Kerala 683112, India
India

Benny Antony
Research and Development Laboratory, Arjuna Natural Extracts Ltd., Nalam Mile, Kulakadu Road, Erumathala, Keezhmad, Kerala 683112, India


Article Tools



Refbacks

  • There are currently no refbacks.