A STABILITY INDICATING UV SPECROPHOTOMETRIC METHOD FOR DETERMINATION OF METOCLOPRAMIDE HYRDROCHLORIDE


Anjali Macchindra Gorde, U A Deokate

Abstract


A stability indicating method has been developed for specific determination of Metoclopramide HCl in bulk by UV spectrophotometry in presence of its degradation products. The method is simple, accurate, precise, and robust. Linearity range for the method is 10-50µg/ml at detection wavelength of 272 nm. The LOD and LOQ values were found to be 3.26µg/ml and 9.89µg/ml respectively.

 


Keywords


Metoclopramide hydrochloride, Stability indicating, UV Bulk, Forced degradation.

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About this article

Title

A STABILITY INDICATING UV SPECROPHOTOMETRIC METHOD FOR DETERMINATION OF METOCLOPRAMIDE HYRDROCHLORIDE

Keywords

Metoclopramide hydrochloride, Stability indicating, UV Bulk, Forced degradation.

Date

01-10-2014

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 6, Issue 9, 2014 Page: 394-397

Online ISSN

0975-1491

Statistics

228 Views | 182 Downloads

Authors & Affiliations

Anjali Macchindra Gorde
Department of Pharmaceutical Chemistry, Government College of Pharmacy, Aurangabad, Maharashtra, India 431005
India

U A Deokate
Department of Pharmaceutical Chemistry, Government College of Pharmacy, Aurangabad, Maharashtra, India 431005
India


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