CHRONIC KIDNEY DISEASE – A MULTI-CENTER STUDY IN KARACHI, PAKISTAN


Farah Saeed, Mansoor Ahmad, Syed Mahboob Alam, Kausar Perveen

Abstract


Objective: Chronic kidney disease is growing at alarming rate in developing countries like Pakistan. The aim of the study was to find out the major factors leading to this disease and to carry out the comparative analysis of the effectiveness of allopathic and homoeopathic medicines in treatment of chronic kidney disease.

Methods: A multi-center study was carried out in five different centers from 2009-2014. The study was carried out by interviewing the patients, noting down their vitals and reviewing their records. Evaluation of the data was done considering age, sex and co-morbidities associated with renal failure.

Results: Significant results were observed. Patients of age groups 46 to 60 (48%) and 30 to 45 (21%) were found to suffer more from chronic kidney disease. Hypertension was found as the most frequently occurring co-morbidity along with chronic renal failure followed by diabetes.

Conclusion: The current study will be beneficial in bringing awareness in general public and thereby reducing the increasing burden of end-stage kidney disease.


Keywords


Urea, creatinine, glomerular filtration rate, allopathic, homoeopathic

| PDF | HTML |

References


Levey AS, de Jong PE, Coresh J, El Nahas M, Astor BC, Matsushita K, et al. The definition, classification, and prognosis of chronic kidney disease: a KDIGO controversies conference report. Kidney Int 2011;80:17–28.

Sakhuja V, Sud K. End-stage renal disease in India and Pakistan: the burden of disease and management issue. Kidney Int 2003;63:S115-S-8.

Jessani S, Bux R, Jafar TH. Prevalence, determinants, and management of chronic kidney disease in Karachi, Pakistan–a community-based cross-sectional study. BMC Nephrol 2014;15:1-9.

Alam A, Amanullah F, Baig-Ansari N, Lotia-Farrukh I, Khan FS. Prevalence and risk factors of kidney disease in urban Karachi: baseline findings from a community cohort study. BMC Res Notes 2014;7:1-11.

Farah Saeed. Studies on allopathic and homeopathic medicines used for the cure of kidney impairment especially in dialysis patients. Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, Pakistan; 2014.

Jungers P, Chauveau P, Bandin O. Hyperhomocysteinemia is associated with atherosclerotic occlusive arterial accidents in predialysis chronic renal failure patients. Miner Electrolyte Metab 1997;23:170-3.

Aghakhani N, Sharif F, Molazem Z, Habibzadeh H. Content analysis and qualitative study of hemodialysis patients, family experience and perceived social support. Iran Red Crescent Med J 2014;16:e13748.

Murali R, Sathyanarayana D, Muthusethupathy MA. Assessment of quality of life in chronic kidney disease patients using the kidney disease quality of life-short form TM questionnaire in the Indian population: a community-based study. Asian J Pharm Clin Res 2015;8:271-4.

Jha V, Chugh KS. Dialysis in developing countries: priorities and obstacles. Nephrology (Carlton) 1996;2:65-72.

Kurokawa K, Nangaku M, Saito A, Inagi R, Miyata T. Current issues and future perspectives of chronic renal failure. J Am Soc Nephrol 2002;13:S3–S6.

Modi GK, Jha V. The incidence of end-stage renal disease in India: a population-based renal disease in India: a population-based study. Kidney Int 2006;70:2131-3.

Mani MK. The management of end-stage renal disease in India. Artif Organs 1998;22:182-6.

Agarwal R. Hypertension and survival in chronic hemodialysis patients-past lessons and future opportunities. Kidney Int 2005;67:1-13.

Sakhuja V, Jha V, Ghosh AK. Chronic renal failure in India. Nephrol Dial Transplant 1994;9:871-2.

Kronenberg F. Emerging risk factors and markers of chronic kidney disease progression. Nat Rev Nephrol 2009;5:677-89.

Thorsteinsdottir B, Swetz KM, Albright RC. The ethics of chronic dialysis for the older patient: time to reevaluate the norms. Clin J Am Soc Nephrol 2015;10:2094-9.

Alverstrand A, Gutierrez A, Bucht A, Bergstrom J. Reduction of blood pressure retards the progression of chronic renal failure in man. Nephrol Dial Transplant 1988;3:624-31.

Brazy PC, Stead WW, Fitzwilliam JF. Progression of renal insufficiency: the role of blood pressure. Kidney Int 1989;35:670-4.

Meyrier A, Buchet P, Simon P, Fernet M, Rainfray M, Callard P. Atheromatous renal disease. Am J Med 1988;85:139-46.

Walker WG. Hypertension-related renal injury; a major contributor to end-stage renal disease. Am J Kidney Dis 1993;22:164-74.

Striker GE. Report on workshop to develop management recommendations for the prevention of progression in chronic renal disease. Nephrol Dial Transplant 1995;10:290-2.




About this article

Title

CHRONIC KIDNEY DISEASE – A MULTI-CENTER STUDY IN KARACHI, PAKISTAN

Keywords

Urea, creatinine, glomerular filtration rate, allopathic, homoeopathic

DOI

10.22159/ijpps.2017v9i12.21240

Date

01-12-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 9, Issue 12, 2017 Page: 170-174

Online ISSN

0975-1491

Statistics

20 Views | 4 Downloads

Authors & Affiliations

Farah Saeed
Department of Pharmacognosy, Dow College of Pharmacy, Dow University of Health Sciences, Ojha Campus, Karachi-Pakistan
Pakistan

Mansoor Ahmad
Research Institute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Karachi-Pakistan

Syed Mahboob Alam
Basic Medical Sciences Institute, Jinnah Post Graduate Medical College, Karachi-PakistanBasic Medical Sciences Institute, Jinnah Post Graduate Medical College, Karachi-Pakistan

Kausar Perveen
Department of Sociology, University of Karachi, Karachi-Pakistan


Article Tools



Refbacks

  • There are currently no refbacks.