SERUM LIPID LEVELS IN PERIODONTITIS PATIENTS: A CASE-CONTROL STUDY


M. A. Adil Ahmed, Judyangel D., Rajathi R., Rafiya S., Pooja Kumari, Pragadeeswari D.

Abstract


Objective: We aimed to evaluate serum lipid levels in periodontitis patients and compared with healthy subjects.

Methods: A case-control study was conducted among 30 participants in the age group of 35-60 y, including 15 subjects in case group with community periodontal index (CPI) score of ≥2 and 15 subjects in the control group with a CPI score of ≤ 1 based on their periodontal status. Fasting blood samples were taken for measurement of lipid profiles, including total cholesterol, triglyceride (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) using an enzymatic method. Odds ratio and independent t-test at *p=0.05 significance level were calculated.

Results: Periodontitis patients were 4.1 times at risk to have high triglyceride, 1.3 times at risk to have high total cholesterol and 0.3times at risk to have higher HDL. Independent t-test showed higher total cholesterol/HDL ratio (*p=0.033) and lowered HDL levels (*p=0.027) in periodontitis patients.

Conclusion: Periodontitis group has significantly higher total cholesterol/high-density lipoprotein ratio and lower high-density lipoprotein levels when compared to the healthy group.


Keywords


Periodontitis, Serum lipid levels, Cardiovascular disease, Total cholesterol, High-density lipoprotein, Low-density lipoprotein, Very low-density lipoprotein, Triglycerides

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About this article

Title

SERUM LIPID LEVELS IN PERIODONTITIS PATIENTS: A CASE-CONTROL STUDY

Keywords

Periodontitis, Serum lipid levels, Cardiovascular disease, Total cholesterol, High-density lipoprotein, Low-density lipoprotein, Very low-density lipoprotein, Triglycerides

DOI

10.22159/ijpps.2018v10i2.23701

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 10, Issue 2, 2018 Page: 171-173

Online ISSN

0975-1491

Authors & Affiliations

M. A. Adil Ahmed
Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Chennai 600119, Tamilnadu, India
India

Judyangel D.
Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Chennai 600119, Tamilnadu, India
India

Rajathi R.
Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Chennai 600119, Tamilnadu, India
India

Rafiya S.
Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Chennai 600119, Tamilnadu, India
India

Pooja Kumari
Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Chennai 600119, Tamilnadu, India
India

Pragadeeswari D.
Department of Public Health Dentistry, Sathyabama Dental College and Hospital, Chennai 600119, Tamilnadu, India
India


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