ANTIBIOTICS PRESCRIPTION PATTERN IN RURAL AREA OF BANGLADESH: A CROSS-SECTIONAL STUDY IN DEBIDWAR UPAZILA OF COMILLA DISTRICT


Umme Salma Khanam, Kazi Nuruddin Al Masud, Tahmid Khurshed, Utsha Chakma

Abstract


Objective: The study was aimed to evaluate the antibiotic prescription pattern by physicians in the area of study.

Methods: This cross-sectional observational study was carried out with a self-designed standard questionnaire by manual data collection over a three months period at the Debidwar Upazila of Comilla District. The data were collected by directly interviewing the participants. Microsoft Excel 2010 was used for the analysis of the collected data.

Results: Out of 242 patients, 60.74% of patients were male, 39.26% of patients were female. Majority of the patients (50%) belonged to age group 9 to 20 and in terms of profession, 53.30% were students. Among the previous disease history, hypertension (20.25%) was found at the dominant position. Common cold (28.95%) was the frequent reason for visiting doctor and ciprofloxacin was prescribed to 30.17% patients (Male: 21.90%, Female: 8.26%). Before prescribing anti-bacterial agents or any other agents, only 23.55% patients were recommended diagnostic tests and in 81.81% cases, physicians simply prescribed medicine by his/her own assumption and culture and sensitivity test was recommended and done for 18.18% patients.

Conclusion: Prescription of broad-spectrum antibiotics for common cold and diarrhea, prescribing antibiotics or medicine based on presumption was the clear indications of irrational antibiotics use and inappropriate prescription pattern.

 


Keywords


Antibiotics, Prescription pattern, Diagnostic tests, Culture, and sensitivity test

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References


Bishwas M, Roy DN, Tajmim A, Rajib SS, Hossain M, Farzana F, et al. Prescription antibiotics for outpatients in Bangladesh: a cross-sectional health survey conducted in three cities. Ann Clin Microbiol Antimicrob 2014;13:15.

Fahad BM, Matin A, Shill MC, Asish KD. Antibiotic usage at a primary health care unit in Bangladesh. Med J Aust 2010;3:414–21.

Biswas M, Roy DN, Rahman MM, Islam M, Masud Parvez GM, Haque MU, et al. Doctor’s prescribing trends of antibiotics for outpatients in Bangladesh: a cross-sectional health survey conducted in three districts. Int J Pharm Sci Res 2015;6:669-75.

Gould IM. Antibiotic resistance: the perfect storm. Int J Antimicrob Agents 2009;34:52–5.

Baktygul K, Marat B, Ashirali Z, Harun-Or-rashid M, Sakamoto J. An assessment of antibiotic prescribed at the secondary health-care level in the kyrgyz republic. Nagoya J Med Sci 2011;73:157–68.

Hadi U, Duerink DO, Lestari ES, Nagelkerke NJ, Keuter M, HuisIn't Veld D, et al. Audit of antibiotic prescribing in two governmental teaching hospitals in Indonesia. Clin Microbiol Infect 2008;14:698–707.

Sumpradit N, Chongtrakul P, Anuwong K, Pumtong S, Kongsomboon K, Butdeeman P, et al. Antibiotics smart use: a workable model for promoting the rational use of medicines in Thailand. Bull WHO 2012;90:905–13.

Hashemi S, Nasrollah A, Rajabi M. Irrational antibiotic prescribing: a local issue or global concern? EXCLI J 2013;12:384-95.

Harbarth S, Albrich W, Brun-Buisson C. Outpatient antibiotic use and prevalence of antibiotic resistant pneumococci in france and germany: a sociocultural perspective. Emerg Infect Dis 2002; 8:1460–7.

Vazquez LagoJ, Lopez Vazquez P, Lopez Duran A, Taracido Trunk M, Figueiras A. Attitudes of primary care physicians to the prescribing of antibiotics and antimicrobial resistance: a qualitative study from Spain. Fam Pract 2011; 29:352–60.

Cadieux G, Tamblyn R, Dauphinee D, Libman M. Predictors of inappropriate antibiotic prescribing among primary care physicians. Can Med Assoc J 2007;177:877–83.

Ali MH, Kalima P, Maxwell SRJ. Failure to implement hospital antimicrobial prescribing guidelines: a comparison of two UK academic centers. J Antimicrob Chemother 2006;57:959–62.

Banoo S, Bell D, Bossuyt P, Herring A, Mabey D, Poole F, et al. Evaluation of diagnostic tests for infectious diseases: general principles. Nat Rev Microbiol 2006;4:21-31.

Bangladesh Population Census, Bangladesh Bureau of Statistics. Cultural survey report of Debidwar Upazila; 2001. Available from: http://www.bbs.gov.bd/cultural survey report.html. [Last accessed 24 Apr 2018].

Shankar RP, Partha P, Shenoy NK, Easow JM, Brahmadathan KN. Prescribing patterns of antibiotics and sensitivity patterns of common microorganisms in the internal medicine ward of a teaching hospital in Western Nepal: A prospective study. Ann Clin Microbiol Antimicrob 2003;2:7.

Sharma M, Eriksson B, Marrone G, Dhaneria S, Lundborg CS. Antibiotic prescribing in two private sector hospitals; one teaching and one non-teaching: a cross-sectional study in Ujjain, India. BMC Infect Dis 2012;12:155.

Alshakka M, Said K, Babakri M, Ansari M, Aldhubhani A, Hassali MA, et al. A study on antibiotics prescribing pattern at outpatient department in four hospitals in aden-yemen. JPPCM 2016;2:88-93.

Louie TJ. Ciprofloxacin: an oral quinolone for the treatment of infections with gram-negative pathogens. Committee on antimicrobial agents. Canadian infectious disease society. Can Med Assoc J 1994;150:669-76.

Danish Health and Medicines Authority. Copenhagen, Denmark. Guidelines on prescribing antibiotics For physicians and others in Denmark 2013;1:1–9.

The NHS in Rotherham. Antimicrobial protocol for the Management of Infection in Primary Care; 2017.

Gwimile JJ, Shekalaghe SA, Kapanda GN, Kisanga ER. Antibiotic prescribing practice in the management of a cough and/or diarrhoea in moshi municipality, northern tanzania: cross-sectional descriptive study. Pan Afr Med J 2012;12:103.

Chowdhury MK, Siddique AA, Sarkar PK, Haque M, Biswas PK, Biswas S, et al. Pattern of antibiotic use in different departments of Dhaka medical college hospital. J Med (Bangladesh) 2015;16:35–8.

Hertfordshire Partnership University NHS Foundation Trust. Antimicrobial Prescribing Guidelines in Adults; 2015.




About this article

Title

ANTIBIOTICS PRESCRIPTION PATTERN IN RURAL AREA OF BANGLADESH: A CROSS-SECTIONAL STUDY IN DEBIDWAR UPAZILA OF COMILLA DISTRICT

Keywords

Antibiotics, Prescription pattern, Diagnostic tests, Culture, and sensitivity test

DOI

10.22159/ijpps.2018v10i12.29437

Date

01-12-2018

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 10, Issue 12, 2018 Page: 36-40

Online ISSN

0975-1491

Authors & Affiliations

Umme Salma Khanam
Department of Pharmacy, BRAC University, Dhaka, Bangladesh
Bangladesh

Kazi Nuruddin Al Masud
Department of Pharmacy, BRAC University, Dhaka, Bangladesh
Bangladesh

Tahmid Khurshed
Department of Pharmacy, BRAC University, Dhaka, Bangladesh
Bangladesh

Utsha Chakma
Department of Pharmacy, BRAC University, Dhaka, Bangladesh
Bangladesh


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