• Ndanusa Abdullahi Hassan Departmentof Biology, Faculty of Science, Universiti Brunei Darussalam, Brunei Darussalam
  • Rohini Karunakaran Unit of Biochemistry, Faculty of Medicine, AIMST University, Semeling, Bedong, Malaysia
  • Suleiman Abdulmumin Department of Biological science, Faculty of Science, Nigerian Defense Academy Kaduna, Nigerian


Consumption of fruits and vegetables fight against oxidative damage by inhibiting or reducing free radicals and reactive oxygen species. Mimosa pudica is a perennial herb and belongs to the family Fabaceae. Epidemiological studies have shown that M. pudica contains metabolites such as phenols and flavonoid compounds which possess pharmacological properties such as antidiabetic, antimicrobial, antiulcer, antidepressants and anti-inflammatory. Ecological studies have shown that M. pudica grows in all types of soil which can survive in soil with low nutrient concentration. It usually requires disturbed soil to establish itself. It is commonly seen in the wastelands and along roadsides, which is an ethnomedical plant that may be used in managing various types of disease. Valuable information and literature on M. pudica are analysed and consulted using a different database such as Google Scholar, Google, Science Direct, Web of Science, Academic Journals and Pubmed. This review article summarises the pharmacological properties of M. pudica.

Keywords: Mimosa pudica, Reactive oxygen species, Anti-diabetic, Anti-inflammatory, Antimicrobial


Download data is not yet available.

Author Biography

Rohini Karunakaran, Unit of Biochemistry, Faculty of Medicine, AIMST University, Semeling, Bedong, Malaysia

Associate Professor

Faculty of Medicine

AIMST University


1. Chattopadhyay MK. Bacterial cryoprotectants. Reson 2002;7:59–63.
2. Ndanusa AH, Rohini Karunakaran, Uma Sankar A, Khin Mar Aye. Anti-diabetic effect of Zingiber officinale on sprague-dawley rats. Int J Pharma Phytol Res 2016;8:1940-3.
3. Dragan S, Nicola T, Molina R, Ursoniu S, Kumar A, Nimade S, et al. Role of multi-component functional foods in the complex treatment of patients with advanced breast cancer. Rev Med Chir Soc Med Nat Iasi 2007;111:877–84.
4. Ndanusa AH, Rohini Karunakaran, Uma Sankar A, Khin Mar Aye. Anti-inflammatory effect of Zingiber officinale on sprague dawley rats. Asian J Pharm Clin Res 2017;10:353–35.
5. Chukwu O, Ahuchaogu A, Ukaogo P, Obike A, Echeme J. Antifungal activity of Mimosa pudica, Isolation and NMR characterization of bioactive components. Asian J Chem Sci 2017;10:1–5.
6. Rohini K, Srikumar P. Therapeutic role of coumarins and coumarin-related compounds. J Thermodyn Catal 2014;5:1–3.
7. McDonald S, Prenzler PD, Antolovich M, Robards K. Phenolic content and antioxidant activity of olive extracts. Food Chem 2001;73:73–84.
8. Zhang J, Yuan K, Zhou W, Zhou J, Yang P. Studies on the active components and antioxidant activities of the extracts of Mimosa pudica Linn. from Southern China. Pharmacogn Mag 2011;7:35.
9. Adesegun SA, Anyika NE, Adekoya TO, Essien SG. Antibacterial and antioxidant investigations of Hallealedermannii leaf extract. Indian J Sci Technol 2012;5:1885–7.
10. Ganguly M, Devi N, Mahanta R, Borthakur MK. Effect of Mimosa pudica root extract on vaginal oestrous and serum hormones for the screening of antifertility activity in albino mice. Contracept 2007;76:482–5.
11. Venkateshwarlu G, Vijayabhaskar K, Pavankumar G, Kiran Kumar P, Harishbabu K, Malothu R. Wound healing activity of Mimosa Pudica in albino Wistar rats. J Chem Pharm Res 2011;3:56–60.
12. Joseph B, George J, Mohan J. Pharmacology and traditional uses of Mimosa pudica. Int J Pharm Sci Drug Res 2013;5:4.
13. Coimbra A, Magnanini A. Considerations sobre Mimosa pudica no combate a arosao superficial. Anucio Braz Econ Floresta Inst Nac Pinho Braz; 1953. p. 131–6.
14. Bhakuni DS, Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN. Screening of Indian plants for biological activity. Indian J Exp Biol 1969;7:250–62.
15. Zaware BB, Chaudhari S, Shinde MT. An overview of Mimosa pudica Linn.? chemistry and pharmacological profile. Res J Pharm Biol Chem Sci 2014;5:757–61.
16. Uehlein N, Kaldenhoff R. Aquaporins and plant leaf movements. Ann Bot 2008;101:1–4.
17. Yao H, Xu Q, Yuan M. Actin dynamics mediate the changes of calcium level during the pulvinus movement of Mimosa pudica. Plant Signal Behav 2008;3:954–60.
18. Patro G, Kumar Bhattamisra S, Kumar Mohanty B. Effects of Mimosa pudica L. leaves extract on anxiety, depression and memory. Avicenna J Phytomed 2016;6:696–710.
19. Varnika S, Ashish S, Imran A. A review on ethnomedical and traditional uses of Mimosa pudica. Int Res J Pharm 2012;3:41–4.
20. Bendgude RD, Maniyar MG, Kondawar MS, Patil SB, Hirave RV. The anti-helminthic activity of leaves of Mimosa pudica. Int Institutional Pharm Life Sci 2012;2:120–5.
21. Pratap Chandra, Deepak V, Sai Krishna, Saniya Fathima, Ameena Thaha, Jeenitha Raj. Analysis of phytochemical constituents and anthelmintic activity of leaf extracts of Mimosa pudica L. Asian J Biomed Pharm Sci 2018;8:2249-622.
22. Azmi L, Manish KS, Ali Kamal A. Pharmacological and biological overview on Mimosa pudica linn. Int J Pharm Life Sci 2011;2:1226–34.
23. Ayan Purkayastha, Pinuki Chakravarty, Babul Dewan. Evaluation of hepatoprotective activity of the ethanolic extract of leaves of Mimosa pudica linn in carbon tetrachloride-induced hepatic injury in albino rats. Int J Basic Clin Pharmacol 2016;5:496-501.
24. Kokane DD, More RY, Kale MB, Nehete MN, Mehendale PC, Gadgoli CH. Evaluation of wound healing activity of root of Mimosa pudica. J Ethnopharmacol 2009;124:311–5.
25. Jagetia GC, Lyngdoh R, Lalramchuana, Borah BK. Mimosa pudica (Lajwanti) accelerates repair and regeneration of deep dermal excision wound in swiss albino mice. Int J Complement Alt Med 2017;9:00293.
26. Hindmarch I. Expanding the horizons of depression: beyond the monoamine hypothesis. Hum Psychopharmacol 2001;16:203–18.
27. Molina M, Contreras CM, Tellez-Alcantara P. Mimosa pudica may possess antidepressant actions in the rat. Int J Phytother Phytopharm 1999;6:319–23.
28. Irfan Sajid, Bijan Kumar Karmaker, Zamiul R, Islam MM, M Ekramul H. CNS depressant and antinociceptive activities of the aerial parts of Mimosa pudica. Eur J Appl Sci 2013;5:127–33.
29. Takagi K, Watanabe M, Saito H. Studies of the spontaneous movement of animals by the hole cross test; effect of 2-dimethylaminoethanol and its acyl esters on the central nervous system. Japan J Pharmacol 1971;21:797–810.
30. Robert H, Howland M. General health, health care utilisation, and medical comorbidity in dysthymia. Int J Psychiatry Med 1993;23:211–38.
31. Bum EN, Soudi S, Ayissi ER, Dong C, Lakoulo NH, Maidawa F, et al. Anxiolytic activity evaluation of four medicinal plants from cameroon. Afr J Tradit Complement Altern Med 2011;8:130–9.
32. Sarris J, Panossian A, Schweitzer I, Stough C, Scholey A. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence. Eur Neuropsychopharmacol J Eur Coll Neuropsychopharmacol 2011;21:841–60.
33. Sowmya A, Ananthi T. Hypolipidemic activity of Mimosa pudica linn on butter induced hyperlipidemia in rats. Asian J Res Pharm Sci 2011;1:123–6.
34. Yupparach P, Konsue A. Hypoglycemic and hypolipidemic activities of ethanolic extract from Mimosa pudica L. in normal and streptozotocin-induced diabetic rats. Pharmacog J 2017;9:834-7.
35. Sia F, Vejayan J, Jamuna A, Ambu S. Efficacy of tannins from Mimosa pudica and tannic acid in neutralising cobra (Najakaouthia) venom. J Venom Anim Toxins Trop Dis 2011;17:42–8.
36. Elango V, Carolin Oliver Raghu PS. Antiulcer activity of the leaf ethanolic extract of Mimosa pudica in Rats. Hygeia J D Med 2012;4:34-40.
37. Vinothapooshan G, Sundar K. Anti-ulcer activity of Mimosa pudica leaves against gastric ulcer in rats. Res J Pharm Biol Chem Sci 2010;1:606–14.
38. Goli V, Bhaskar KV, Macharla SP, Jimmidi Bhaskar, Devi PS, Ramchander T. Effects of anti-Inflammatory activity of Mimosa pudica. Asian J Pharm Res 2011;1:69–71.
39. Nair PV, Bindu Latha RN. Anti-inflammatory activity of hydroalcoholic extract of Mimosa pudica whole plant in rats. Int J Basic Clin Pharmacol 2017;6:518–22.
40. Yupparach P, Konsue A. Hypoglycemic and hypolipidemic activities of ethanolic extract from Mimosa pudica L. in normal and Streptozotocin-induced diabetic rats. Pharmacogn J 2017;9:834–7.
41. Tamilarasi T, Ananthi T. Phytochemical analysis and anti-microbial activity of Mimosa pudica Linn. Res J Chem Sci 2012;2:72–4.
42. Chukwu O, Ahuchaogu A, Ukaogo P, Obike A, Echeme J. Antifungal activity of Mimosa pudica, isolation and NMR characterization of bioactive components. Asian J Chem Sci 2017;2:1–5.
43. Rajalakshmi K, N Banu. Antimicrobial activity of natural chlorophyllin from endangered medicinal plant Mimosa Pudica L. Int J Pharm Pharc Sci 2016;8:387-9.
44. Mahesh AG, Jayadevappa H, Mahadevan KM, Shastry RA, Habbu PV, Sayeswara HA. Isolation and characterisation of secondary metabolite from Habenaria intermedia D. Don for screening of hepatoprotective potential against carbon tetrachloride induced toxicity in albino rat liver. Int J Curr Pharm Res 2014;7:57-61.
517 Views | 741 Downloads
How to Cite
Abdullahi Hassan, N., R. Karunakaran, and S. Abdulmumin. “A REVIEW ON THE PHARMACOLOGICAL AND TRADITIONAL PROPERTIES OF MIMOSA PUDICA”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 11, no. 3, Mar. 2019, pp. 12-16, doi:10.22159/ijpps.2019v11i3.30452.
Review Article(s)