• ALMOHAMMADI AMEEN Associate Professor of Clinical Pharmacy Saudi Arabia
  • JUNAID SUHAIL Associate Professor of Clinical Pharmacy Saudi Arabia
  • SHORBATLI LOUJAIN Associate Professor of Clinical Pharmacy Saudi Arabia
  • AL-SOMALI AMAL Associate Professor of Clinical Pharmacy Saudi Arabia



Premenstrual syndrome, Dysmenorrhea, Menstrual irregularity, Menarche, OTC analgesics, Menstrual pain


Objective: The study focuses on assessing the incidence of menstrual irregularity among young women and the factors for a disturbance with the rationale to assess the use of analgesic drugs during Premenstrual Syndrome (PMS).

Methods: A cross-sectional study was used. A total of 2500 randomly selected young female between the age of 11 and 30 y completed the study questionnaire to assess lifestyle pattern, variations in menstrual pattern, perceived stress, and to capture information about their menstrual cycle and related problems. In addition, the questionnaire assessed the use of analgesics for PMS.

Results: 2481 participants completed the questionnaire. The mean age of participants’ menarche was 12.85±1.432 y. The prevalence of menstrual irregularities was 25.0 % (n=621) and about 8.5% (n=211) of respondents had severe pain that was not relieved by the use of analgesics. On the other hand, 50.9 % (n=1262) reported severe pain that was relieved by analgesics. A total of 1279 (51.6 %) of participants in this study used Over The Counter (OTC) analgesics to relieve PMS.

Conclusion: Dysmenorrhea is the most common complaint among young females in Saudi Arabia. Low Body Mass Index (BMI), sedentary lifestyle, stress and early age of menarche are the most important factors associated with menstrual irregularities. Proper education programs and awareness among young girls about their menstrual health, and the provision of guidance in choosing effective analgesics and treatment options for dysmenorrhea are highly recommended.


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Burrows A, Johnson S. Girls' experiences of menarche and menstruation. J Reprod Infant Psychol 2005;23:235-49.

Chang YT, Chen YC, Hayter M, Lin ML. Menstrual and menarche experience among pubescent female students in taiwan: implications for health education and promotion practice. J Clin Nurs 2009;18:2040-8.

Thomas F, Renaud F, Benefice E, De Meeüs T, Guegan JF. International variability of ages at menarche and menopause: patterns and main determinants. Huma Biol 2001;73:271-90.

Kaplowitz P. Pubertal development in girls: secular trends. Curr Opin Obstet Gynecol 2006;18:487-91.

Bean JA, Leeper JD, Wallace RB, Sherman BM, Jagger H. Variations in the reporting of menstrual histories. Am J Epidemiol 1979;109:181-5.

Rebuffe Scrive M, Enk L, Crona N, Lonnroth P, Abrahamsson L, Smith U, et al. Fat cell metabolism in different regions in women. Effect of the menstrual cycle, pregnancy, and lactation. J Clin Investig 1985;75:1973-6.

Harlow SD, Campbell OM. Epidemiology of menstrual disorders in developing countries: a systematic review. BJOG: An Int J Obstet Gynecol 2004;111:6-16.

Harel Z. Dysmenorrhea in adolescents and young adults: etiology and management. J Pediatr Adolesc Gynecol 2006;19:363-71.

Kettaneh APS, Todesco M. Good policy and practice booklet no. 9: puberty education and menstrual hygiene management. Paris: United Nations Educational, Scientific and Cultural Organization; 2014.

Always. Tips and advice: “the talk”. Available from: [Last accessed on 15 Oct 2014]

Pettersson F, Fries H, Nillius SJ. Epidemiology of secondary amenorrhea: I. Incidence and prevalence rates. Am J Obstet Gynecol 1973;117:80-6.

Baker ER, Mathur RS, Kirk RF, Williamson HO. Female runners and secondary amenorrhea: correlation with age, parity, mileage, and plasma hormonal and sex-hormone-binding globulin concentrations. Fertil Steril 198;36:183-7.

Fries H, Nillius SJ, Pettersson F. Epidemiology of secondary amenorrhea: II. A retrospective evaluation of etiology with special regard to psychogenic factors and weight loss. Am J Obstet Gynecol 1974;118:473-9.

Drew FL. The epidemiology of secondary amenorrhea. J Clin Epidemiol 1961;14:396-407.

Loucks AB, Horvath SM. Athletic amenorrhea: a review. Med Sci Sport Exerc 1985;17:56-72.

American Academy of Pediatrics, American College of Obstetricians and Gynecologists. Menstruation in girls and adolescents: using the menstrual cycle as a vital sign. Pediatr 2006;118:2245-50.

Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav 1983;24:385-96.

Campbell MA, McGrath PJ. Use of medication by adolescents for the management of menstrual discomfort. Arch Pediatr Adolesc Med 1997;151:905-13.

Boscolo P, Mason L. Topic knowledge, text coherence, and interest: How they interact in learning from instructional texts. J Exp Educ 2003;71:126-48.

Moos RH. The development of a menstrual distress questionnaire. Psychosom Med 1968;30:853-67.

Groves RM, Presser S, Dipko S. The role of topic interest in survey participation decisions. Public Opin Q 2004;68:2-31.

Al-Nozha MM, Al-Mazrou YY, Al-Maatouq MA, Arafah MR, Khalil MZ, Khan NB, et al. Obesity in Saudi Arabia. Saudi Med J 2005;26:824-9.

Montero P, Bernis C, Fernandez V, Castro S. Influence of body mass index and slimming habits on menstrual pain and cycle irregularity. J Biosoc Sci 1996;28:315-23.

Chang PJ, Chen PC, Hsieh CJ, Chiu LT. Risk factors on the menstrual cycle of healthy taiwanese college nursing students. Aust N Z J Obstet Gynaecol 2009;49:689-94.

Cross GB, Marley J, Miles H, Willson K. Changes in nutrient intake during the menstrual cycle of overweight women with premenstrual syndrome. Br J Nutr 2001;85:475-82.

Poppitt SD, McCormack D, Buffenstein R. Short-term effects of macronutrient preloads on appetite and energy intake in lean women. Physiol Behav 1998;64:279-85.

Fenster L, Waller K, Chen J, Hubbard AE, Windham GC, Elkin E, et al. Psychological stress in the workplace and menstrual function. Am J Epidemiol 1999;149:127-34.

Yamamoto K, Okazaki A, Sakamoto Y, Funatsu M. The relationship between premenstrual symptoms, menstrual pain, irregular menstrual cycles, and psychosocial stress among Japanese college students. J Physiol Anthropol 2009;28:129-36.

Barnes Josiah D, Augustin A. Secular trend in the age at menarche in Haiti. Am J Hum Biol 1995;7:357-62.

Zegeye DT, Megabiaw B, Mulu A. Age at menarche and the menstrual pattern of secondary school adolescents in northwest Ethiopia. BMC Women's Health 2009;9:29.

Thomas KD, Okonofua FE, Chiboka O. A study of the menstrual patterns of adolescents in Ile-Ife, Nigeria. Obstet Gynecol Int J 1990;33:31-4.

Loukid M, Baali A, Hilali MK. Secular trend in age at menarche in Marrakesh (Morocco). Ann Hum Biol 1996;23:333-5.

Babay Z. Age at menarche and the reproductive performance of Saudi women. Age 2004;15:14.

Pomerleau CS, Cole PA, Lumley MA, Marks JL, Pomerleau OF. Effects of menstrual phase on nicotine, alcohol, and caffeine intake in smokers. J Subst Abus 1994;6:227-34.

Cakir M, Mungan I, Karakas T, Girisken I, Okten A. Menstrual pattern and common menstrual disorders among university students in turkey. Pediatr Int 2007;49:938-42.

Wong LP, Khoo EM. Dysmenorrhea in a multiethnic population of adolescent Asian girls. Int J Obstet Gynecol 2010;108:139-42.

Houston AM, Abraham A, Huang Z, D'Angelo LJ. Knowledge, attitudes, and consequences of menstrual health in urban adolescent females. J Pediatr Adolesc Gynecol 2006;19:271-5.

Campbell EM, Peterkin D, O'grady K, Sanson Fisher R. Premenstrual symptoms in general practice patients. Prevalence and treatment. J Reprod Health Med 1997;42:637-46.

Dars S, Sayed K, Yousufzai Z. Relationship of menstrual irregularities to BMI and nutritional status in adolescent girls. Pak J Med Sci 2014;30:141.



How to Cite

AMEEN, A., J. SUHAIL, S. LOUJAIN, and A.-S. AMAL. “ASSESSMENT OF MENSTRUAL HEALTH AND ANALGESICS USAGE IN YOUNG AGE WOMEN”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 12, no. 2, Feb. 2020, pp. 38-42, doi:10.22159/ijpps.2020v12i2.36423.



Original Article(s)